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Catalog Number:
14822
CAS Number:
252554-79-3
Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH
Purity:
95 - 105% (Assay by titration)
Synonym(s):
Fmoc-Ala-Thr[ψ(Me,Me)Pro]-OH, (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylicacid
Antibiotic
Documents
$66.80 /1G
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Product Information

Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its effectiveness in solid-phase peptide synthesis. Its unique structure, including the Psi(Me,Me)Pro modification, enhances the stability and bioactivity of peptides, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry.

This compound is particularly beneficial for the synthesis of cyclic peptides and peptidomimetics, which are essential in developing therapeutics targeting various diseases. Its ability to facilitate the formation of stable peptide bonds while maintaining the integrity of sensitive functional groups allows for greater flexibility in designing novel compounds. Researchers can leverage Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH to explore new avenues in drug discovery, particularly in the development of targeted therapies and biologically active molecules.

Synonyms
Fmoc-Ala-Thr[ψ(Me,Me)Pro]-OH, (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylicacid
CAS Number
252554-79-3
Purity
95 - 105% (Assay by titration)
Molecular Formula
C25H28N2O6
Molecular Weight
452.51
MDL Number
MFCD03490490
PubChem ID
75627341
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-Ala-Thr[ψ(Me,Me)Pro]-OH, (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylicacid
CAS Number
252554-79-3
Purity
95 - 105% (Assay by titration)
Molecular Formula
C25H28N2O6
Molecular Weight
452.51
MDL Number
MFCD03490490
PubChem ID
75627341
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Ala-Thr[Psi(Me,Me)Pro] is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in the development of peptide-based therapeutics, providing researchers with a tool to design and optimize drug candidates with enhanced stability and bioactivity.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the modification of proteins to study structure-function relationships, enabling scientists to explore the effects of specific amino acid substitutions on protein behavior.
  • Diagnostics: Fmoc-Ala-Thr[Psi(Me,Me)Pro] is utilized in the development of diagnostic assays, particularly in the detection of biomarkers through peptide-based methods, enhancing the accuracy of medical diagnostics.

Citations