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Catalog Number:
04281
N-(2-Chlorotrityl resin)-glycine N-hydroxysuccinimide ester
Synonym(s):
2-Chlorotrityl resin-Gly-OSu
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$60.39 /1G
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Product Information

N-(2-Chlorotrityl resin)-glycine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This resin-bound reagent offers a unique approach for the efficient coupling of glycine derivatives, making it an essential tool for researchers in the fields of medicinal chemistry and biochemistry. Its ability to facilitate the formation of peptide bonds under mild conditions enhances its appeal, particularly in the synthesis of complex peptides and proteins, which are crucial for drug development and therapeutic research.

The compound's unique structure allows for selective reactions, minimizing side products and improving overall yield. Its application extends to the development of targeted drug delivery systems, where precise conjugation of therapeutic agents to biomolecules is necessary. Researchers benefit from its high reactivity and stability, making it an ideal choice for various applications, including the synthesis of peptide-based vaccines and diagnostic agents. With its robust performance and reliability, N-(2-Chlorotrityl resin)-glycine N-hydroxysuccinimide ester stands out as a valuable asset in modern chemical research.

Synonyms
2-Chlorotrityl resin-Gly-OSu
MDL Number
MFCD01074996
Substitution
0.2 - 1.0 mmol/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
General Information
Synonyms
2-Chlorotrityl resin-Gly-OSu
MDL Number
MFCD01074996
Substitution
0.2 - 1.0 mmol/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-(2-Chlorotrityl resin)-glycine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development.
  • Bioconjugation: It facilitates the attachment of biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the effectiveness of diagnostic tools and therapeutics.
  • Solid-Phase Synthesis: Used in solid-phase peptide synthesis, it offers a streamlined method for producing peptides, reducing time and increasing yield compared to traditional methods.
  • Drug Delivery Systems: The compound can be incorporated into drug delivery systems, improving the stability and bioavailability of therapeutic agents.
  • Research in Immunology: It plays a role in creating immunogenic peptides for vaccine development, helping to advance research in infectious diseases and cancer.

Citations