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Catalog Number:
04231
Fmoc-S-trityl-L-cysteine-2-chlorotrityl resin
Synonym(s):
Fmoc-L-Cys(Trt)-2-chlorotrityl resin
Documents
$40.00 /1G
Pack Size Availability Price
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Product Information

Fmoc-S-trityl-L-cysteine-2-chlorotrityl resin is a highly specialized resin used in solid-phase peptide synthesis, particularly for the efficient and selective synthesis of peptides containing cysteine residues. This resin features a unique combination of Fmoc (9-fluorenylmethoxycarbonyl) protection and trityl (Tr) groups, which provide excellent stability and protection during the synthesis process. With a functional loading of 0.3 - 0.9 meq/g and a mesh size of 200 - 400, it ensures optimal performance in various peptide synthesis applications, allowing for precise control over the synthesis conditions.

Researchers and industry professionals can leverage this resin for the development of peptides with specific functionalities, such as those used in drug discovery, vaccine development, and the creation of peptide-based therapeutics. Its robust structure minimizes side reactions, enhancing yield and purity, making it a preferred choice for high-quality peptide synthesis. The versatility and reliability of Fmoc-S-trityl-L-cysteine-2-chlorotrityl resin make it an invaluable tool for advancing peptide chemistry and biochemistry research.

Synonyms
Fmoc-L-Cys(Trt)-2-chlorotrityl resin
MDL Number
MFCD00801374
Appearance
Yellow beads
Substitution
0.3 - 0.8 meq/g
Mesh Size
200 - 400
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
General Information
Synonyms
Fmoc-L-Cys(Trt)-2-chlorotrityl resin
MDL Number
MFCD00801374
Appearance
Yellow beads
Substitution
0.3 - 0.8 meq/g
Mesh Size
200 - 400
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-trityl-L-cysteine-2-chlorotrityl resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin is essential for solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its high loading capacity ensures that larger peptides can be synthesized without compromising yield.
  • Drug Development: In pharmaceutical research, it aids in the development of peptide-based drugs, providing a reliable method for attaching various functional groups that enhance drug efficacy.
  • Bioconjugation: The resin facilitates the attachment of peptides to other biomolecules, such as antibodies or enzymes, which is crucial for creating targeted therapies in cancer treatment.
  • Protein Engineering: Researchers use this resin to modify cysteine residues in proteins, enabling the introduction of new functionalities that can improve protein stability and activity.
  • Analytical Chemistry: It serves as a platform for the synthesis of peptide libraries, which are invaluable for screening and identifying potential drug candidates in high-throughput settings.

Citations