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Catalog Number:
04039
Nα-Boc-Nim-trityl-L-histidine Merrifield resin (0.25 - 1.0 meq/g, 100 - 200 mesh)
Synonym(s):
Boc-L-His(Trt)-Merrifield resin
Documents
$30.35 /1G
Pack Size Availability Price
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Product Information

Na-Boc-Nim-trityl-L-histidine Merrifield resin is a specialized resin used extensively in peptide synthesis and drug development. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which is crucial for the selective protection of amino groups during the synthesis process. With a capacity of 0.25 - 1.0 meq/g and a mesh size of 100 - 200, it is designed to facilitate efficient coupling reactions, making it an ideal choice for researchers focusing on solid-phase peptide synthesis. The trityl group enhances the stability of the resin, allowing for longer reaction times without degradation, which is particularly beneficial in complex peptide synthesis.

This resin is particularly advantageous for the synthesis of histidine-containing peptides, which are important in various biological processes and therapeutic applications. Its unique properties enable high yields and purity of the final product, making it a preferred choice for professionals in pharmaceutical research and development. Researchers can leverage this resin to streamline their workflows, reduce purification steps, and enhance the overall efficiency of peptide synthesis.

Synonyms
Boc-L-His(Trt)-Merrifield resin
MDL Number
MFCD00801363
Substitution
0.25 - 1.0 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-L-His(Trt)-Merrifield resin
MDL Number
MFCD00801363
Substitution
0.25 - 1.0 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-trityl-L-histidine Merrifield resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin serves as a solid support for the synthesis of peptides through solid-phase methods, allowing for efficient assembly of complex peptide chains.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, enabling researchers to create novel compounds for various medical applications.
  • Bioconjugation: The resin can be used to attach peptides to other biomolecules, facilitating the creation of targeted drug delivery systems and diagnostic agents.
  • Protein Engineering: Researchers utilize this resin to modify histidine residues in proteins, enhancing their stability and functionality for industrial or therapeutic purposes.
  • Research in Catalysis: It is also explored in the field of catalysis, where modified peptides can act as catalysts in various chemical reactions, providing a greener alternative to traditional methods.

Citations