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Catalog Number:
02773
Boc-L-phenylalanine Merrifield resin (0.3 - 1.2 meq/g, 100 - 200 mesh)
Synonym(s):
Boc-L-Phe-Merrifield resin
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Boc-L-phenylalanine Merrifield is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound, known for its protective Boc (tert-butyloxycarbonyl) group, facilitates the efficient assembly of peptides by preventing unwanted side reactions during the synthesis process. Its unique structure allows for easy incorporation into various peptide sequences, making it an essential building block for researchers focused on developing novel therapeutics and biologically active compounds.

In addition to its role in peptide synthesis, Boc-L-phenylalanine Merrifield is also employed in the production of peptide-based drugs and in the study of protein interactions. Its stability and compatibility with various coupling reagents enhance its utility in solid-phase peptide synthesis (SPPS), streamlining the production of complex peptides. Researchers and industry professionals benefit from its ability to improve yields and purity in peptide synthesis, making it a valuable asset in both academic and industrial laboratories.

Synonyms
Boc-L-Phe-Merrifield resin
MDL Number
MFCD00801205
Substitution
0.3 - 1.2 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Boc-L-Phe-Merrifield resin
MDL Number
MFCD00801205
Substitution
0.3 - 1.2 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-phenylalanine Merrifield is widely utilized in research focused on

  • Peptide Synthesis: This compound is crucial in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its protective group facilitates the stepwise addition of amino acids, enhancing yield and purity.
  • Drug Development: In pharmaceutical research, it serves as a building block for designing novel peptide-based drugs. Its unique properties can lead to improved bioavailability and specificity in therapeutic applications.
  • Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules. This is essential in creating targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: Researchers employ Boc-L-phenylalanine Merrifield in the modification of proteins to study structure-function relationships. This aids in understanding protein interactions and developing engineered proteins with desired characteristics.
  • Research in Neuroscience: Its application in synthesizing neuropeptides helps in studying neurological pathways and developing treatments for neurodegenerative diseases, showcasing its relevance in cutting-edge research.

Citations