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Catalog Number:
02763
Nα-Boc-Nim-2,4-dinitrophenyl-L-histidine Merrifield resin (0.25 - 0.7 meq/g, 100 - 200 mesh)
Synonym(s):
Nα-Boc-Nim-2,4-dinitrophenyl-L-histidineMerrifield resin (0.25 - 0.7 meq/g, 100 - 200 mesh)
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Na-Boc-Nim-2,4-dinitrophenyl-L-histidine Merrifield is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This derivative of histidine features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Its unique structure allows for selective reactions, facilitating the development of complex peptides and proteins.

In practical applications, Na-Boc-Nim-2,4-dinitrophenyl-L-histidine Merrifield is particularly valuable in the synthesis of peptide-based therapeutics and vaccines, where precise control over amino acid sequences is crucial. Its ability to undergo various coupling reactions while maintaining the integrity of the histidine side chain opens new avenues for the design of targeted drug delivery systems and diagnostic tools. Researchers appreciate its compatibility with automated synthesizers, streamlining the peptide synthesis process and improving overall efficiency.

Synonyms
Nα-Boc-Nim-2,4-dinitrophenyl-L-histidineMerrifield resin (0.25 - 0.7 meq/g, 100 - 200 mesh)
MDL Number
MFCD00801362
Substitution
0.25 - 0.7 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Nα-Boc-Nim-2,4-dinitrophenyl-L-histidineMerrifield resin (0.25 - 0.7 meq/g, 100 - 200 mesh)
MDL Number
MFCD00801362
Substitution
0.25 - 0.7 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-2,4-dinitrophenyl-L-histidine Merrifield is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the development of novel pharmaceuticals by facilitating the design of peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of diagnostics and therapeutics.
  • Research in Immunology: It is applied in the study of immune responses, particularly in developing vaccines or immunotherapies that require precise amino acid modifications.
  • Analytical Chemistry: This chemical aids in the development of analytical techniques for detecting and quantifying peptides, improving the accuracy of biochemical assays.

Citations