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Catalog Number:
04205
Nα-Fmoc-Nim-trityl-D-histidine 4-alkoxybenzyl alcohol resin (0.3-0.8 meq/g, 100-200 mesh)
Synonym(s):
Fmoc-D-His(Trt)-Wang resin
Documents
$95.00 /1G
Pack Size Availability Price
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Product Information

Na-Fmoc-Nim-trityl-D-histidine 4-alkoxybenzyl alcohol resin is a specialized resin used primarily in peptide synthesis and solid-phase synthesis applications. This compound serves as a versatile building block for the development of peptides and proteins, enabling researchers to create complex structures with high precision. Its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, facilitating the stepwise assembly of peptides. The incorporation of trityl and D-histidine enhances the stability and solubility of the resin, making it an excellent choice for various synthetic pathways.

This resin is particularly beneficial in the pharmaceutical and biotechnology industries, where it is employed in the synthesis of therapeutic peptides and drug candidates. Its ability to provide high yields and purity during synthesis makes it a preferred choice among researchers. Additionally, the resin's compatibility with automated synthesizers streamlines the peptide synthesis process, saving time and resources. Overall, Na-Fmoc-Nim-trityl-D-histidine 4-alkoxybenzyl alcohol resin is an essential tool for professionals seeking to advance their research in peptide chemistry.

Synonyms
Fmoc-D-His(Trt)-Wang resin
MDL Number
MFCD00801240
Appearance
Pale yellow beads
Substitution
0.3-0.8 meq/g
Mesh Size
100-200 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Fmoc-D-His(Trt)-Wang resin
MDL Number
MFCD00801240
Appearance
Pale yellow beads
Substitution
0.3-0.8 meq/g
Mesh Size
100-200 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nim-trityl-D-histidine 4-alkoxybenzyl alcohol resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin is essential for solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its unique structure facilitates the attachment and detachment of amino acids, streamlining the synthesis process.
  • Drug Development: In pharmaceutical research, this resin aids in the development of peptide-based drugs. Its ability to form stable linkages enhances the formulation of therapeutic agents targeting specific diseases.
  • Bioconjugation: The resin is used in bioconjugation techniques, where peptides are linked to other biomolecules. This is crucial for creating targeted drug delivery systems, improving the efficacy of treatments.
  • Research in Cancer Therapy: Researchers utilize this resin to develop peptides that can inhibit cancer cell growth. Its application in creating specific inhibitors can lead to breakthroughs in cancer treatment.
  • Protein Engineering: In the field of protein engineering, the resin is employed to modify proteins for enhanced functionality. This is particularly beneficial in creating proteins with improved stability and activity for various industrial applications.

Citations