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Catalog Number:
01909
Nα-Fmoc-Nim-trityl-L-histidine 4-alkoxybenzyl alcohol resin (0.3-0.8 meq/g, 100-200 mesh)
Synonym(s):
Fmoc-L-His(Trt)-Wang resin
Documents
$51.18 /1G
Pack Size Availability Price
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Product Information

Na-Fmoc-Nim-trityl-L-histidine 4-alkoxybenzyl alcohol is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This derivative of histidine features a protective Fmoc group and a trityl group, making it an excellent choice for researchers focused on developing complex peptides and proteins. Its unique structure allows for selective deprotection, facilitating the synthesis of bioactive compounds with enhanced stability and solubility.

In pharmaceutical research, this compound is particularly valuable for creating targeted drug delivery systems and studying protein interactions. Its ability to form stable complexes with various biomolecules opens avenues for innovative therapeutic applications, including cancer treatment and enzyme inhibition studies. Researchers benefit from its high purity and reliability, ensuring consistent results in experimental setups. With its significant role in advancing peptide chemistry, Na-Fmoc-Nim-trityl-L-histidine 4-alkoxybenzyl alcohol stands out as an essential tool for professionals in the field.

Synonyms
Fmoc-L-His(Trt)-Wang resin
MDL Number
MFCD00801255
Appearance
Pale to yellow beads
Substitution
0.3-0.8 meq/g (UV spectroscopy)
Mesh Size
100-200 mesh (Microscopic method)
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Fmoc-L-His(Trt)-Wang resin
MDL Number
MFCD00801255
Appearance
Pale to yellow beads
Substitution
0.3-0.8 meq/g (UV spectroscopy)
Mesh Size
100-200 mesh (Microscopic method)
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nim-trityl-L-histidine 4-alkoxybenzyl alcohol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its application in drug formulation helps in enhancing the stability and solubility of active pharmaceutical ingredients, making it valuable in the pharmaceutical industry for creating effective medications.
  • Bioconjugation: The compound is used in bioconjugation processes, where it facilitates the attachment of drugs to antibodies or other biomolecules, improving targeted delivery systems in cancer therapy.
  • Research in Biochemistry: It plays a significant role in biochemistry research, particularly in studying protein interactions and functions, which is essential for understanding various biological processes.
  • Material Science: The compound can be utilized in the development of smart materials, where its unique properties contribute to creating responsive systems for sensors and drug delivery applications.

Citations