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Catalog Number:
06793
Fmoc-L-glutamic acid े-tert-butyl ester-2-chlorotrityl resin (0.3 - 0.8 meq/g, 200 - 400 mesh)
Synonym(s):
Fmoc-L-Glu(OtBu)-2-chlorotrityl resin
Documents
$30.00 /1G
Pack Size Availability Price
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Product Information

Fmoc-L-glutamic acid g-tert-butyl ester-2-chlorotrityl resin is a specialized resin widely utilized in peptide synthesis and solid-phase synthesis applications. This compound serves as an essential building block for the production of peptides, offering a robust platform for researchers and industry professionals engaged in drug development and biochemical research. Its unique structure allows for efficient coupling reactions, making it ideal for synthesizing complex peptides with high purity and yield. The tert-butyl ester protects the carboxylic acid group, facilitating selective deprotection under mild conditions, which is crucial for maintaining the integrity of sensitive peptide sequences.

This resin is particularly advantageous in combinatorial chemistry and high-throughput screening, where rapid synthesis and evaluation of peptide libraries are required. Its compatibility with various coupling reagents and solvents enhances its versatility, making it suitable for diverse applications in pharmaceutical research, including the development of peptide-based therapeutics and vaccines. Researchers can rely on this resin for its stability and efficiency, ensuring that their peptide synthesis processes are both effective and reproducible.

Synonyms
Fmoc-L-Glu(OtBu)-2-chlorotrityl resin
Molecular Weight
0.0
MDL Number
MFCD03792270
Substitution
0.3 - 0.8 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Fmoc-L-Glu(OtBu)-2-chlorotrityl resin
Molecular Weight
0.0
MDL Number
MFCD03792270
Substitution
0.3 - 0.8 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid g-tert-butyl ester-2-chlorotrityl resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin is essential for solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently and with high purity.
  • Drug Development: In pharmaceutical research, it aids in the development of peptide-based drugs, providing a platform for modifying peptide sequences to enhance therapeutic effects.
  • Bioconjugation: The resin can be used to attach peptides to other biomolecules, facilitating the creation of targeted drug delivery systems and improving the efficacy of treatments.
  • Protein Engineering: It supports the design and synthesis of modified proteins, which can be crucial for studying protein functions and interactions in various biological processes.
  • Research in Neuroscience: The compound is valuable in synthesizing neuropeptides, which play significant roles in brain function and can lead to advancements in understanding neurological disorders.

Citations