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Catalog Number:
02492
Nα-Boc-Nim-4-toluenesylfonyl-L-histidine 4-oxymethylphenylacetamidomethyl resin
Synonym(s):
Boc-L-His(Tos)-PAM resin
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Na-Boc-Nim-4-toluenesylfonyl-L-histidine 4-oxymethylphenylacetamidomethyl is a specialized compound that plays a significant role in the field of organic synthesis and pharmaceutical research. This compound is recognized for its unique structure, which combines protective groups that enhance its stability and reactivity. Its applications are particularly relevant in the synthesis of peptide-based drugs, where the protection of amino groups is crucial for maintaining the integrity of the peptide during various chemical reactions. Researchers utilize this compound to facilitate the selective modification of histidine residues, which can lead to the development of novel therapeutic agents with improved efficacy and reduced side effects.

In addition to its role in drug development, Na-Boc-Nim-4-toluenesylfonyl-L-histidine 4-oxymethylphenylacetamidomethyl is also valuable in biochemical studies, particularly in the exploration of enzyme-substrate interactions. Its ability to serve as a versatile building block allows for the creation of complex molecules that can be tailored for specific biological activities. This compound stands out due to its compatibility with various coupling reactions, making it an essential tool for chemists and researchers aiming to innovate in the fields of medicinal chemistry and biochemistry.

Synonyms
Boc-L-His(Tos)-PAM resin
MDL Number
MFCD00801202
Substitution
0.25-0.80 meq/g
Mesh Size
100-200
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-L-His(Tos)-PAM resin
MDL Number
MFCD00801202
Substitution
0.25-0.80 meq/g
Mesh Size
100-200
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-4-toluenesylfonyl-L-histidine 4-oxymethylphenylacetamidomethyl is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing chemists to selectively modify amino acids without affecting others, which is crucial for creating complex peptides.
  • Drug Development: It plays a role in the development of pharmaceuticals, particularly in designing compounds that target specific biological pathways, enhancing drug efficacy and reducing side effects.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps link biomolecules to therapeutic agents, improving the delivery and effectiveness of treatments in targeted therapies.
  • Research in Cancer Therapy: Its application in cancer research is notable, as it aids in the development of novel compounds that can inhibit tumor growth, providing potential new avenues for treatment.
  • Analytical Chemistry: This chemical is also utilized in analytical methods to study protein interactions, helping researchers understand complex biological systems and disease mechanisms.

Citations