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Catalog Number:
42370
CAS Number:
501-53-1
Benzyl chloroformate (30-35% in Toluene)
Purity:
30 - 35% (Assay by titration)
Synonym(s):
Carbobenzoxy Chloride (30-35% in Toluene), Cbz chloride (30-35% in Toluene), Chloroformic acid benzyl ester (30-35% in Toluene), Cbz-Cl (30-35% in Toluene)
Hazmat
Documents
$30.00 /25ML
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Product Information

Benzyl chloroformate is a versatile reagent widely utilized in organic synthesis, particularly in the formation of carbamates and esters. This compound, often found in a 30-35% solution in toluene, serves as an essential building block in the pharmaceutical and agrochemical industries. Its ability to introduce the benzyl protecting group makes it invaluable for protecting amines and alcohols during multi-step synthesis processes. Researchers appreciate its efficiency in facilitating reactions while minimizing side products, thereby enhancing overall yield and purity.

In addition to its applications in synthetic organic chemistry, benzyl chloroformate is also employed in the production of various fine chemicals and intermediates. Its unique reactivity allows for the selective modification of functional groups, making it a preferred choice for chemists looking to streamline their workflows. With its proven track record in both academic and industrial settings, benzyl chloroformate stands out as a reliable reagent that can significantly improve the efficiency of chemical synthesis.

Synonyms
Carbobenzoxy Chloride (30-35% in Toluene), Cbz chloride (30-35% in Toluene), Chloroformic acid benzyl ester (30-35% in Toluene), Cbz-Cl (30-35% in Toluene)
CAS Number
501-53-1
Purity
30 - 35% (Assay by titration)
Molecular Formula
C8H7ClO2
Molecular Weight
0
MDL Number
MFCD00000640
PubChem ID
10387
Density
0.96 (Lit.)
Appearance
Colorless to Almost colorless clear liquid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Carbobenzoxy Chloride (30-35% in Toluene), Cbz chloride (30-35% in Toluene), Chloroformic acid benzyl ester (30-35% in Toluene), Cbz-Cl (30-35% in Toluene)
CAS Number
501-53-1
Purity
30 - 35% (Assay by titration)
Molecular Formula
C8H7ClO2
Molecular Weight
0
MDL Number
MFCD00000640
PubChem ID
10387
Density
0.96 (Lit.)
Appearance
Colorless to Almost colorless clear liquid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Benzyl chloroformate is widely utilized in research focused on:

  • Organic Synthesis: It serves as a versatile reagent for the protection of amines and alcohols, allowing chemists to selectively modify functional groups without affecting others.
  • Pharmaceutical Development: This compound is crucial in the synthesis of various pharmaceuticals, particularly in creating intermediates for drug formulations, enhancing the efficiency of drug discovery processes.
  • Polymer Chemistry: Used in the production of polycarbonate and other polymers, it contributes to the development of materials with desirable mechanical and thermal properties.
  • Analytical Chemistry: It aids in the derivatization of compounds for improved detection and analysis in chromatography, making it easier for researchers to identify and quantify substances.
  • Bioconjugation: Benzyl chloroformate is employed in bioconjugation techniques, allowing for the attachment of biomolecules to surfaces or other molecules, which is vital in diagnostics and therapeutic applications.

Citations