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Catalog Number:
00144
CAS Number:
28920-43-6
Fmoc-Chloride
Purity:
≥ 99% (HPLC)
Synonym(s):
9-Fluorenylmethyl chloroformate, Chloroformic acid 9-fluorenylmethyl ester
Hazmat
Documents
$18.50 /5G
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Product Information

Fmoc-Chloride is a versatile reagent widely utilized in peptide synthesis and organic chemistry. This compound, known for its role as a protecting group for amino acids, enables the selective modification of functional groups, facilitating the construction of complex peptide sequences. Its stability under various reaction conditions makes it an ideal choice for researchers aiming to streamline their synthesis processes. Fmoc-Chloride is particularly valuable in solid-phase peptide synthesis, where it allows for the efficient assembly of peptides while minimizing side reactions.

In addition to its applications in peptide synthesis, Fmoc-Chloride is also employed in the development of pharmaceuticals and bioconjugates, enhancing the delivery and efficacy of therapeutic agents. Its unique properties, such as ease of removal under mild conditions, set it apart from other protecting groups, making it a preferred choice among chemists. With its proven track record in both academic and industrial settings, Fmoc-Chloride continues to be an essential tool for advancing research and development in the field of chemistry.

Synonyms
9-Fluorenylmethyl chloroformate, Chloroformic acid 9-fluorenylmethyl ester
CAS Number
28920-43-6
Purity
≥ 99% (HPLC)
Molecular Formula
C15H11ClO2
Molecular Weight
258.7
MDL Number
MFCD00001138
PubChem ID
34367
Melting Point
61 - 65 °C
Appearance
White to off-white or light yellow crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
9-Fluorenylmethyl chloroformate, Chloroformic acid 9-fluorenylmethyl ester
CAS Number
28920-43-6
Purity
≥ 99% (HPLC)
Molecular Formula
C15H11ClO2
Molecular Weight
258.7
MDL Number
MFCD00001138
PubChem ID
34367
Melting Point
61 - 65 °C
Appearance
White to off-white or light yellow crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Chloride is widely utilized in research focused on:

  • Peptide Synthesis: It serves as a key reagent in the solid-phase synthesis of peptides, allowing for the protection of amino groups during the synthesis process, which enhances yield and purity.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, which can be crucial for targeting specific biological pathways or diseases.
  • Bioconjugation: Fmoc-Chloride is employed in bioconjugation techniques, facilitating the attachment of peptides to various biomolecules, aiding in the development of targeted therapies.
  • Analytical Chemistry: It is utilized in the preparation of standards for chromatographic techniques, helping researchers to accurately analyze peptide compositions in complex mixtures.
  • Material Science: In the development of functional materials, it can be used to modify surfaces with peptide sequences, which can enhance biocompatibility for medical devices.

Citations