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Catalog Number:
14260
CAS Number:
330645-87-9
O-(1H-6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
Purity:
≥ 99% (HPLC)
Synonym(s):
HCTU
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Product Information

O-(1H-6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is a versatile reagent widely utilized in organic synthesis, particularly in the field of peptide and nucleic acid chemistry. This compound serves as an effective coupling agent, facilitating the formation of amide bonds in the synthesis of peptides, which is crucial for developing pharmaceuticals and biotechnological applications. Its unique structure allows for enhanced reactivity and selectivity, making it a preferred choice among researchers looking to streamline their synthetic processes.

Additionally, this compound is recognized for its stability and ease of handling, which are significant advantages in laboratory settings. Its application extends to the synthesis of complex organic molecules, where it aids in the efficient coupling of various functional groups. Researchers and industry professionals can benefit from its ability to improve yields and reduce reaction times, ultimately leading to more efficient workflows in chemical synthesis.

Synonyms
HCTU
CAS Number
330645-87-9
Purity
≥ 99% (HPLC)
Molecular Formula
C11H15CIF6N5OP
Molecular Weight
413.69
MDL Number
MFCD04973268
PubChem ID
42624899
Melting Point
178 - 193 ºC
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
HCTU
CAS Number
330645-87-9
Purity
≥ 99% (HPLC)
Molecular Formula
C11H15CIF6N5OP
Molecular Weight
413.69
MDL Number
MFCD04973268
PubChem ID
42624899
Melting Point
178 - 193 ºC
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-(1H-6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as an efficient coupling reagent in peptide synthesis, enhancing yield and purity, which is crucial for pharmaceutical development.
  • Bioconjugation: It is employed in bioconjugation reactions to link biomolecules, such as proteins and nucleic acids, facilitating the creation of targeted drug delivery systems.
  • Fluorescent Labeling: The chemical is used in the preparation of fluorescent probes, aiding in biological imaging and diagnostics, which are essential in research and clinical settings.
  • Polymer Chemistry: It acts as a reagent in the modification of polymers, improving their properties for applications in coatings and materials science.
  • Environmental Analysis: This compound is utilized in analytical chemistry for detecting and quantifying pollutants, contributing to environmental monitoring and safety assessments.

Citations