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Catalog Number:
12968
CAS Number:
4457-32-3
4-Nitrobenzyl chloroformate
Purity:
≥ 98% (HPLC)
Synonym(s):
4-Nitrobenzyl chlorocarbonate, Chloroformic acid 4-nitrobenzyl ester
Hazmat
Documents
$22.03 /5G
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Product Information

4-Nitrobenzyl chloroformate is a versatile reagent widely utilized in organic synthesis, particularly in the preparation of various esters and amides. This compound serves as an effective protecting group for alcohols and amines, facilitating the selective functionalization of complex molecules. Its unique nitro group enhances electrophilicity, making it an excellent choice for reactions involving nucleophiles. Researchers and industry professionals appreciate its ability to streamline synthetic pathways, thus improving yields and reducing reaction times.

In addition to its role in organic synthesis, 4-Nitrobenzyl chloroformate is also employed in the development of pharmaceuticals and agrochemicals. Its application in the synthesis of biologically active compounds underscores its importance in medicinal chemistry. The compound’s stability and reactivity profile make it a preferred choice for chemists looking to optimize their synthetic strategies. With its proven track record in enhancing reaction efficiency, 4-Nitrobenzyl chloroformate is an invaluable tool for those engaged in advanced chemical research and development.

Synonyms
4-Nitrobenzyl chlorocarbonate, Chloroformic acid 4-nitrobenzyl ester
CAS Number
4457-32-3
Purity
≥ 98% (HPLC)
Molecular Formula
C8H6ClNO4
Molecular Weight
215.6
MDL Number
MFCD00007375
PubChem ID
78205
Appearance
Light yellow liquid/solid
Conditions
Store at 0-8 °C
General Information
Synonyms
4-Nitrobenzyl chlorocarbonate, Chloroformic acid 4-nitrobenzyl ester
CAS Number
4457-32-3
Purity
≥ 98% (HPLC)
Molecular Formula
C8H6ClNO4
Molecular Weight
215.6
MDL Number
MFCD00007375
PubChem ID
78205
Appearance
Light yellow liquid/solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Nitrobenzyl chloroformate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in the synthesis of various organic molecules, particularly in the formation of esters and amides, which are essential in pharmaceuticals and agrochemicals.
  • Peptide Chemistry: It is commonly used in the protection of amino groups during peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: The compound plays a crucial role in the modification of drug candidates, enhancing their stability and bioavailability, which is vital in the pharmaceutical industry.
  • Analytical Chemistry: It is employed in the derivatization of compounds for improved detection and quantification in chromatographic techniques, aiding researchers in accurate analysis.
  • Material Science: This chemical is utilized in the development of polymeric materials, contributing to the creation of advanced materials with specific properties for various industrial applications.

Citations