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Catalog Number:
02322
CAS Number:
524-38-9
N-Hydroxyphthalimide
Purity:
≥ 99% (Assay)
Synonym(s):
2-Hydroxy-1H-isoindole-1,3(2H-dione, Phthaloxime
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Product Information

N-Hydroxyphthalimide is a versatile compound widely recognized for its applications in organic synthesis and as a reagent in various chemical reactions. This compound, also known as N-Hydroxyphthalimide, is particularly valued for its ability to act as a mild oxidizing agent, making it an essential tool in the synthesis of amines and other nitrogen-containing compounds. Researchers and industry professionals utilize N-Hydroxyphthalimide in the preparation of pharmaceuticals, agrochemicals, and fine chemicals, where its unique properties facilitate the formation of complex molecular structures with high efficiency.

One of the notable advantages of N-Hydroxyphthalimide is its ability to selectively oxidize primary amines to their corresponding oximes, which can then be further transformed into various functional groups. This selectivity not only enhances the yield of desired products but also minimizes the formation of by-products, making it a preferred choice in synthetic pathways. Additionally, its stability and ease of handling contribute to its appeal in laboratory and industrial settings, ensuring that it meets the rigorous demands of modern chemical processes.

Synonyms
2-Hydroxy-1H-isoindole-1,3(2H-dione, Phthaloxime
CAS Number
524-38-9
Purity
≥ 99% (Assay)
Molecular Formula
C8H5NO3
Molecular Weight
163.13
MDL Number
MFCD00005891
PubChem ID
10665
Melting Point
231-237 ?C
Appearance
Off-white to yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Hydroxy-1H-isoindole-1,3(2H-dione, Phthaloxime
CAS Number
524-38-9
Purity
≥ 99% (Assay)
Molecular Formula
C8H5NO3
Molecular Weight
163.13
MDL Number
MFCD00005891
PubChem ID
10665
Melting Point
231-237 ?C
Appearance
Off-white to yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Hydroxyphthalimide is widely utilized in research focused on:

  • Organic Synthesis: It serves as a key reagent in various organic reactions, particularly in the synthesis of amides and other nitrogen-containing compounds, making it valuable for chemists developing new pharmaceuticals.
  • Photoinitiators: This compound is used as a photoinitiator in UV-curable coatings and inks, enhancing the efficiency of curing processes in the printing and coatings industry.
  • Polymer Chemistry: N-Hydroxyphthalimide is employed in the production of high-performance polymers, offering improved thermal stability and mechanical properties compared to similar compounds.
  • Analytical Chemistry: It is utilized in analytical methods for detecting and quantifying certain metal ions, providing a reliable option for researchers in environmental and materials science.
  • Pharmaceutical Development: The compound plays a role in drug formulation, particularly in creating prodrugs that enhance bioavailability, thus benefiting the pharmaceutical industry in developing effective therapies.

Citations