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Catalog Number:
41756
CAS Number:
5066-94-4
Phenylthiohydantoin-isoleucine (contains PTH-alloisoleucine)
Purity:
≥ 98% (HPLC)
Synonym(s):
5-sec-Butyl-3-phenyl-2-thiohydantoin (containsPTH-alloisoleucine), PTH-isoleucine (contains PTH-alloisoleucine)
Documents
$105.00 /100MG
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Product Information

Phenylthiohydantoin-isoleucine, also known as PTH-isoleucine, is a specialized compound widely utilized in peptide synthesis and amino acid analysis. This compound is particularly valuable in the field of biochemistry for its role in identifying and characterizing amino acids through the Edman degradation method. Its unique structure allows for the selective tagging of isoleucine residues, facilitating the study of protein structure and function. Researchers appreciate its high specificity and reliability, making it an essential tool in proteomics and molecular biology.

In addition to its applications in research, Phenylthiohydantoin-isoleucine is also relevant in pharmaceutical development, where it aids in the synthesis of peptide-based drugs. Its ability to stabilize peptide bonds enhances the efficacy of drug formulations, providing a competitive edge in therapeutic applications. With its proven track record in both academic and industrial settings, this compound stands out for its versatility and effectiveness in advancing scientific research and product development.

Synonyms
5-sec-Butyl-3-phenyl-2-thiohydantoin (containsPTH-alloisoleucine), PTH-isoleucine (contains PTH-alloisoleucine)
CAS Number
5066-94-4
Purity
≥ 98% (HPLC)
Molecular Formula
C13H16N2OS
Molecular Weight
248.34
MDL Number
MFCD00057213
PubChem ID
3034584
Melting Point
178 - 182 °C
Appearance
White to off-white powder
Optical Rotation
[á]20/D = 22 - 26 ° (C=1 in EtOH)
Conditions
Store at RT
General Information
Synonyms
5-sec-Butyl-3-phenyl-2-thiohydantoin (containsPTH-alloisoleucine), PTH-isoleucine (contains PTH-alloisoleucine)
CAS Number
5066-94-4
Purity
≥ 98% (HPLC)
Molecular Formula
C13H16N2OS
Molecular Weight
248.34
MDL Number
MFCD00057213
PubChem ID
3034584
Melting Point
178 - 182 °C
Appearance
White to off-white powder
Optical Rotation
[á]20/D = 22 - 26 ° (C=1 in EtOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phenylthiohydantoin-isoleucine is widely utilized in research focused on:

  • Amino Acid Analysis: This compound is essential for identifying and quantifying amino acids in proteins, particularly isoleucine. It helps researchers in biochemistry and molecular biology to analyze protein structures and functions.
  • Peptide Synthesis: Used in the synthesis of peptides, it aids in creating specific sequences necessary for drug development and therapeutic applications, making it invaluable in pharmaceutical research.
  • Chiral Resolution: The compound plays a role in separating enantiomers, which is crucial in the production of chiral drugs. This ensures that medications are effective and safe for patients.
  • Protein Folding Studies: It assists in understanding protein folding mechanisms, which is vital for developing treatments for diseases caused by misfolded proteins, such as Alzheimer’s.
  • Analytical Chemistry: Employed in chromatographic techniques, it enhances the detection and analysis of complex mixtures, benefiting industries like food safety and environmental monitoring.

Citations