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Catalog Number:
07220
CAS Number:
133373-24-7
Fmoc-N-methyl-O-tert-butyl-L-tyrosine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-N-Me-L-Tyr(tBu)-OH
Documents
$72.31 /250MG
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Product Information

Fmoc-N-methyl-O-tert-butyl-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, including the tert-butyl and methyl groups, enhances solubility and stability, making it an ideal choice for researchers in organic chemistry and biochemistry.

In practical applications, Fmoc-N-methyl-O-tert-butyl-L-tyrosine is particularly valuable in the development of therapeutic peptides and proteins, where precise control over amino acid sequences is crucial. Its use in solid-phase peptide synthesis allows for efficient and high-yield production of complex peptides, which can be further explored for pharmaceutical applications. Researchers appreciate its compatibility with various coupling reagents and its ability to facilitate the synthesis of modified peptides, thus expanding the potential for innovative drug design and development.

Synonyms
Fmoc-N-Me-L-Tyr(tBu)-OH
CAS Number
133373-24-7
Purity
≥ 99% (HPLC)
Molecular Formula
C29H31NO5
Molecular Weight
473.6
MDL Number
MFCD02684471
PubChem ID
85446173
Melting Point
180 - 190 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -49 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-N-Me-L-Tyr(tBu)-OH
CAS Number
133373-24-7
Purity
≥ 99% (HPLC)
Molecular Formula
C29H31NO5
Molecular Weight
473.6
MDL Number
MFCD02684471
PubChem ID
85446173
Melting Point
180 - 190 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -49 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-N-methyl-O-tert-butyl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective groups allow for selective reactions, facilitating the creation of complex peptide structures.
  • Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs. Its stability and compatibility with various reaction conditions make it an ideal candidate for creating therapeutic peptides.
  • Bioconjugation: The compound can be employed in bioconjugation processes, where it helps attach peptides to other biomolecules, enhancing drug delivery systems and improving the efficacy of therapeutic agents.
  • Research in Neuroscience: It plays a role in synthesizing neuropeptides, which are crucial for studying neurological functions and disorders, providing insights into potential treatments for conditions like depression and anxiety.
  • Custom Peptide Libraries: Researchers utilize it to create diverse peptide libraries for screening and identifying new bioactive compounds, aiding in the discovery of novel therapeutics.

Citations