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Catalog Number:
02199
CAS Number:
33099-08-0
Z-N-methyl-L-leucine
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-N-Me-L-Leu-OH
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Product Information

Z-N-methyl-L-leucine is a valuable amino acid derivative recognized for its applications in peptide synthesis and pharmaceutical research. This compound serves as a crucial building block in the development of biologically active peptides, particularly in the design of peptide-based therapeutics. Its unique structure, featuring a methyl group that enhances its stability and bioactivity, makes it an attractive choice for researchers looking to optimize peptide properties.

In the pharmaceutical industry, Z-N-methyl-L-leucine is utilized in the synthesis of various drug candidates, contributing to advancements in treatments for conditions such as cancer and metabolic disorders. Its ability to improve the solubility and permeability of peptides enhances their therapeutic potential, making it a preferred option for formulators. Additionally, this compound is also explored in the field of biochemistry for its role in studying protein interactions and enzyme activity. With its diverse applications and significant benefits, Z-N-methyl-L-leucine stands out as a key ingredient for professionals aiming to innovate in peptide chemistry and drug development.

Synonyms
Z-N-Me-L-Leu-OH
CAS Number
33099-08-0
Purity
≥ 98% (HPLC)
Molecular Formula
C15H21NO4
Molecular Weight
279.3
MDL Number
MFCD00038521
Melting Point
60 - 75 °C
Appearance
White powder
Optical Rotation
[a]20D = -26 ± 2 º (C=1 in DMF)25D = -21 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-N-Me-L-Leu-OH
CAS Number
33099-08-0
Purity
≥ 98% (HPLC)
Molecular Formula
C15H21NO4
Molecular Weight
279.3
MDL Number
MFCD00038521
Melting Point
60 - 75 °C
Appearance
White powder
Optical Rotation
[a]20D = -26 ± 2 º (C=1 in DMF)25D = -21 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-N-methyl-L-leucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its unique structure enhances the stability and bioactivity of the resulting peptides.
  • Drug Development: It plays a crucial role in medicinal chemistry, where it is used to create more effective drug candidates. Researchers appreciate its ability to improve the pharmacokinetic properties of compounds.
  • Biotechnology: In the field of biotechnology, Z-N-methyl-L-leucine is employed in the design of enzyme inhibitors and other biocatalysts, which can lead to more efficient industrial processes.
  • Protein Engineering: This chemical is important in protein engineering applications, where it helps in modifying proteins to enhance their functionality or stability, making it essential for developing novel biotherapeutics.
  • Research on Amino Acid Analogues: It is used in studies investigating amino acid analogues, providing insights into metabolic pathways and potential therapeutic targets in various diseases.

Citations