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Catalog Number:
07966
CAS Number:
110115-07-6
Calpain Inhibitor II
Purity:
≥ 99% (HPLC)
Synonym(s):
Ac-Leu-Leu-Met-aldehyde
Documents
$252.98 /5MG
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Product Information

Calpain Inhibitor II is a potent and selective inhibitor of calpain, a calcium-dependent cysteine protease involved in various cellular processes, including apoptosis and cell signaling. This compound is particularly valuable in research settings focused on neurodegenerative diseases, cancer, and muscle disorders, where calpain activity is often dysregulated. By inhibiting calpain, researchers can explore therapeutic avenues that may mitigate cellular damage and promote cell survival.

In addition to its role in basic research, Calpain Inhibitor II has shown promise in preclinical studies aimed at understanding its effects on muscle regeneration and neuroprotection. Its unique structure allows for specific targeting of calpain, making it a preferred choice over other inhibitors that may lack selectivity. This specificity not only enhances experimental outcomes but also reduces potential off-target effects, making it an essential tool for scientists and industry professionals alike.

Synonyms
Ac-Leu-Leu-Met-aldehyde
CAS Number
110115-07-6
Purity
≥ 99% (HPLC)
Molecular Formula
C19H35N3O4S
Molecular Weight
401.57
MDL Number
MFCD00065506
PubChem ID
4331
Appearance
White to off-white powder
Conditions
Store at -0°C.
General Information
Synonyms
Ac-Leu-Leu-Met-aldehyde
CAS Number
110115-07-6
Purity
≥ 99% (HPLC)
Molecular Formula
C19H35N3O4S
Molecular Weight
401.57
MDL Number
MFCD00065506
PubChem ID
4331
Appearance
White to off-white powder
Conditions
Store at -0°C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Calpain Inhibitor II is widely utilized in research focused on:

  • Neuroscience Research: This compound is crucial for studying neurodegenerative diseases like Alzheimer's, as it helps in understanding calpain's role in neuronal cell death.
  • Cardiovascular Studies: It aids in investigating heart diseases by inhibiting calpain activity, which is linked to cardiac muscle damage during ischemia.
  • Cancer Research: Researchers use it to explore the mechanisms of tumor progression, as calpain is involved in cell migration and invasion in various cancers.
  • Muscle Biology: This inhibitor is applied in studies of muscle atrophy and regeneration, providing insights into muscle diseases and potential therapeutic targets.
  • Pharmaceutical Development: It serves as a lead compound in drug discovery aimed at developing new treatments for conditions associated with calpain dysregulation.

Citations