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Catalog Number:
02693
CAS Number:
2149-70-4
Nω-Nitro-L-arginine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
L-Arg(NO2)-OH
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Product Information

Nw-Nitro-L-arginine is a potent nitric oxide synthase inhibitor that plays a crucial role in various biochemical and pharmacological applications. This compound is widely recognized for its ability to modulate nitric oxide levels in biological systems, making it invaluable in cardiovascular research and studies related to hypertension. Researchers utilize Nw-Nitro-L-arginine to explore its effects on vascular function and to investigate potential therapeutic strategies for conditions associated with excessive nitric oxide production. Its unique properties allow for targeted applications in both in vitro and in vivo studies, providing insights into the mechanisms of nitric oxide signaling.

In addition to its research applications, Nw-Nitro-L-arginine has shown promise in the development of novel treatments for various diseases, including neurodegenerative disorders and inflammatory conditions. By inhibiting nitric oxide synthase, this compound can help regulate physiological processes, offering a pathway for innovative therapeutic interventions. Its versatility and effectiveness make Nw-Nitro-L-arginine a valuable asset for researchers and industry professionals seeking to advance their work in pharmacology and biochemistry.

Synonyms
L-Arg(NO2)-OH
CAS Number
2149-70-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C6H13N5O4
Molecular Weight
219.2
MDL Number
MFCD00007033
PubChem ID
4367
Melting Point
239 - 245 °C
Appearance
White powder or colorless crystals
Optical Rotation
[a]20D = 22 ± 3 ° (C=2 in 2N HCl)
Conditions
Store at RT
General Information
Synonyms
L-Arg(NO2)-OH
CAS Number
2149-70-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C6H13N5O4
Molecular Weight
219.2
MDL Number
MFCD00007033
PubChem ID
4367
Melting Point
239 - 245 °C
Appearance
White powder or colorless crystals
Optical Rotation
[a]20D = 22 ± 3 ° (C=2 in 2N HCl)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nw-Nitro-L-arginine is widely utilized in research focused on

  • Cardiovascular Research: This compound is often used to study nitric oxide synthesis and its effects on blood pressure regulation, providing insights into hypertension treatments.
  • Neuroscience: Researchers employ Nw-Nitro-L-arginine to investigate its role in neurotransmission, particularly in understanding how nitric oxide influences neuronal signaling.
  • Pharmacology: It serves as a valuable tool in drug development, helping to assess the efficacy of new medications targeting vascular and neurological disorders.
  • Biochemistry: The compound is used in enzyme inhibition studies, allowing scientists to explore the mechanisms of arginine metabolism and its implications in various metabolic pathways.
  • Experimental Therapeutics: Nw-Nitro-L-arginine is investigated for potential therapeutic applications in conditions like sepsis and organ failure, where modulation of nitric oxide levels may be beneficial.

Citations