Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02590
CAS Number:
1113-41-3
L-Penicillamine
Purity:
≥ 99% (Assay)
Synonym(s):
L-Pen-OH, L-2-Amino-3-mercapto-3-methylbutanoic acid, H-Pen-OH
Documents
$51.18 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

L-Penicillamine is a versatile thiol compound with significant applications in both pharmaceutical and industrial sectors. Known for its chelating properties, it is widely utilized in the treatment of heavy metal poisoning, particularly lead and copper, by binding to these metals and facilitating their excretion from the body. This makes L-Penicillamine an essential agent in medical settings, particularly for patients suffering from Wilson's disease, where copper accumulation poses serious health risks. Additionally, its role as a disease-modifying antirheumatic drug (DMARD) in the management of rheumatoid arthritis showcases its importance in therapeutic applications, helping to alleviate symptoms and improve quality of life for patients.

Beyond its medical uses, L-Penicillamine is also employed in various industrial processes, including the synthesis of pharmaceuticals and as a reagent in analytical chemistry. Its unique ability to form stable complexes with metal ions enhances its utility in catalysis and material science. Researchers and industry professionals appreciate L-Penicillamine for its multifunctionality and effectiveness, making it a valuable addition to any laboratory or pharmaceutical formulation.

Synonyms
L-Pen-OH, L-2-Amino-3-mercapto-3-methylbutanoic acid, H-Pen-OH
CAS Number
1113-41-3
Purity
≥ 99% (Assay)
Molecular Formula
C5H11NO2S
Molecular Weight
149.2
MDL Number
MFCD00064303
PubChem ID
4727
Melting Point
206 °C (dec.)
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = 61 - 64 ° (C=1 in 1M NaOH)
Conditions
Store at RT
General Information
Synonyms
L-Pen-OH, L-2-Amino-3-mercapto-3-methylbutanoic acid, H-Pen-OH
CAS Number
1113-41-3
Purity
≥ 99% (Assay)
Molecular Formula
C5H11NO2S
Molecular Weight
149.2
MDL Number
MFCD00064303
PubChem ID
4727
Melting Point
206 °C (dec.)
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = 61 - 64 ° (C=1 in 1M NaOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

L-Penicillamine is widely utilized in research focused on

  • Rheumatoid Arthritis Treatment: This compound is commonly prescribed to manage symptoms of rheumatoid arthritis, helping to reduce inflammation and joint pain.
  • Heavy Metal Detoxification: It acts as a chelating agent, effectively binding to heavy metals like lead and mercury, facilitating their removal from the body.
  • Cystinuria Management: L-Penicillamine is used to treat cystinuria, a genetic disorder that leads to kidney stones, by reducing cystine levels in urine.
  • Wilson's Disease Therapy: It plays a crucial role in managing Wilson's disease by promoting copper excretion, thus preventing copper accumulation in the body.
  • Research Applications: In laboratories, it is often used in studies related to protein folding and metal ion interactions, providing insights into biochemical processes.

Citations