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Catalog Number:
02237
CAS Number:
1148-11-4
Z-L-proline
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-L-Pro-OH, (S-Z-pyrrolidine-2-carboxylic acid
Documents
$18.53 /5G
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Product Information

Z-L-proline is a valuable amino acid derivative widely utilized in the synthesis of peptides and pharmaceuticals. This compound is recognized for its unique structural properties, which enhance the stability and bioactivity of peptide chains. Its ability to act as a chiral building block makes Z-L-proline particularly beneficial in asymmetric synthesis, allowing researchers to create compounds with specific stereochemistry. In the pharmaceutical industry, it is often employed in the development of drug candidates, especially those targeting neurological disorders and metabolic diseases.

Moreover, Z-L-proline's role in the production of various bioactive compounds, including enzyme inhibitors and receptor ligands, highlights its significance in medicinal chemistry. Its compatibility with various reaction conditions and ease of incorporation into peptide sequences further solidify its status as a preferred choice among researchers and industry professionals. With its diverse applications and advantages over similar compounds, Z-L-proline stands out as a crucial component in modern chemical synthesis and drug development.

Synonyms
Z-L-Pro-OH, (S-Z-pyrrolidine-2-carboxylic acid
CAS Number
1148-11-4
Purity
≥ 99% (HPLC)
Molecular Formula
C13H15NO4
Molecular Weight
249.27
MDL Number
MFCD00003170
PubChem ID
232388
Melting Point
75 - 78 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -62 ± 2 º (C=2 in AcOH)
Conditions
Store at 0-8 °C.
General Information
Synonyms
Z-L-Pro-OH, (S-Z-pyrrolidine-2-carboxylic acid
CAS Number
1148-11-4
Purity
≥ 99% (HPLC)
Molecular Formula
C13H15NO4
Molecular Weight
249.27
MDL Number
MFCD00003170
PubChem ID
232388
Melting Point
75 - 78 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -62 ± 2 º (C=2 in AcOH)
Conditions
Store at 0-8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the production of cyclic peptides that have significant biological activity.
  • Pharmaceutical Development: It plays a crucial role in drug design, especially in the development of inhibitors for various enzymes, enhancing the efficacy of therapeutic agents.
  • Biochemical Research: Z-L-proline is used in studies exploring protein folding and stability, helping researchers understand the mechanisms behind protein structure and function.
  • Food Industry: It acts as a flavor enhancer and stabilizer in food products, improving taste profiles while maintaining product integrity.
  • Cosmetic Formulations: The compound is incorporated into skincare products for its moisturizing properties, providing benefits like improved skin hydration and texture.

Citations