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Catalog Number:
00775
CAS Number:
13734-34-4
Boc-L-phenylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-L-Phe-OH, (S-2-tert-Butoxycarbonylamino-3-phenylpropionicacid
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Product Information

Boc-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers looking to develop complex peptides. Its unique structure allows for selective reactions, facilitating the incorporation of phenylalanine into various peptide sequences. This capability is particularly valuable in the design of biologically active peptides and drug candidates, where precise amino acid composition is crucial.

In addition to its applications in peptide synthesis, Boc-L-phenylalanine serves as a building block in the development of novel therapeutics and biomaterials. Its hydrophobic nature and aromatic side chain contribute to the stability and functionality of peptides, making it a preferred choice in the pharmaceutical industry. Researchers can leverage Boc-L-phenylalanine to create targeted drug delivery systems or to enhance the bioactivity of peptide-based drugs. With its proven track record in both academic and industrial settings, Boc-L-phenylalanine remains a key compound for advancing peptide chemistry and drug development.

Synonyms
Boc-L-Phe-OH, (S-2-tert-Butoxycarbonylamino-3-phenylpropionicacid
CAS Number
13734-34-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C14H19NO4
Molecular Weight
265.31
MDL Number
MFCD00002663
PubChem ID
269698
Melting Point
80 - 90 °C
Appearance
White powder
Optical Rotation
[a]D20 = +25 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Phe-OH, (S-2-tert-Butoxycarbonylamino-3-phenylpropionicacid
CAS Number
13734-34-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C14H19NO4
Molecular Weight
265.31
MDL Number
MFCD00002663
PubChem ID
269698
Melting Point
80 - 90 °C
Appearance
White powder
Optical Rotation
[a]D20 = +25 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceuticals, Boc-L-phenylalanine is used to create peptide-based drugs. Its incorporation can enhance the bioactivity and stability of therapeutic peptides, making them more effective in treating diseases.
  • Biotechnology: Researchers in biotechnology utilize this compound for the production of modified proteins. By incorporating Boc-L-phenylalanine, scientists can study protein interactions and functions more effectively.
  • Analytical Chemistry: It is employed in various analytical techniques, including chromatography, to separate and identify amino acids and peptides. This application is crucial for quality control in food and pharmaceutical industries.
  • Research in Neuroscience: The compound is used in studies related to neurotransmitter synthesis, particularly in understanding the role of phenylalanine in brain function and its implications in disorders like phenylketonuria.

Citations