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Catalog Number:
33565
CAS Number:
1391586-30-3
Fmoc-4-azido-D-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Phe(4-N3)-OH, Fmoc-p-azido-D-Phe-OH
Documents
$95.60 /100MG
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Product Information

Fmoc-4-azido-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique azido group, which enhances its reactivity and allows for various modifications, making it an essential building block in the creation of complex peptides. Researchers appreciate its ability to facilitate click chemistry reactions, enabling the incorporation of diverse functional groups into peptide structures. This property is particularly beneficial in the development of targeted therapeutics and bioconjugates, where precision and specificity are paramount.

In addition to its applications in medicinal chemistry, Fmoc-4-azido-D-phenylalanine is also valuable in the study of protein interactions and the design of novel biomaterials. Its stability and compatibility with standard peptide synthesis protocols make it an attractive choice for researchers aiming to explore new avenues in drug discovery and development. By leveraging the unique properties of this compound, scientists can create innovative solutions that address complex biological challenges.

Synonyms
Fmoc-D-Phe(4-N3)-OH, Fmoc-p-azido-D-Phe-OH
CAS Number
1391586-30-3
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20N4O4
Molecular Weight
428.5
MDL Number
MFCD00053719
PubChem ID
20674486
Melting Point
162 - 164 °C
Appearance
Off-white crystalline powder
Optical Rotation
[a]D20 = 30 ± 2 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-D-Phe(4-N3)-OH, Fmoc-p-azido-D-Phe-OH
CAS Number
1391586-30-3
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20N4O4
Molecular Weight
428.5
MDL Number
MFCD00053719
PubChem ID
20674486
Melting Point
162 - 164 °C
Appearance
Off-white crystalline powder
Optical Rotation
[a]D20 = 30 ± 2 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-azido-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of azide groups that facilitate further chemical modifications.
  • Click Chemistry: Its azide functionality makes it ideal for click chemistry applications, enabling researchers to create diverse bioconjugates efficiently, which is crucial in drug development and biomolecular research.
  • Bioconjugation: The compound can be used to attach biomolecules, such as proteins or nucleic acids, to surfaces or other molecules, enhancing the functionality of biosensors and diagnostic tools.
  • Drug Development: In pharmaceutical research, it aids in the design of novel therapeutics by allowing for the exploration of structure-activity relationships through the modification of peptide sequences.
  • Fluorescent Labeling: Fmoc-4-azido-D-phenylalanine can be utilized in the development of fluorescently labeled peptides, which are essential for studying protein interactions and cellular processes in live cells.

Citations