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Catalog Number:
30526
CAS Number:
684270-46-0
Nα-Fmoc-Nβ-Azido-L-2,3-diaminopropionic acid Solvate with DIPE
Purity:
≥ 94% (Assay by titration)
Synonym(s):
2-(S)-Fmoc-amino-3-azidopropanoic acid, Fmoc-L-Dap(N3)-OH
Documents
$120.88 /250MG
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Product Information

Na-Fmoc-Nb-Azido-L-2,3-diaminopropionic acid is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This amino acid derivative, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and an azido functional group, serves as a crucial building block in the development of bioactive peptides and pharmaceuticals. Its unique structure allows for selective reactions, making it an ideal candidate for applications in drug discovery and development. Researchers appreciate its stability under various conditions and its compatibility with standard coupling reagents, facilitating efficient synthesis processes.

In addition to its role in peptide synthesis, Na-Fmoc-Nb-Azido-L-2,3-diaminopropionic acid is also employed in click chemistry, enabling the formation of diverse molecular architectures. This compound's azido group can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), a powerful tool for bioconjugation and labeling studies. Its ability to enhance the solubility and bioavailability of peptides further underscores its significance in pharmaceutical formulations. Overall, this compound stands out for its practical applications in research and industry, offering significant advantages in the synthesis of complex biomolecules.

Synonyms
2-(S)-Fmoc-amino-3-azidopropanoic acid, Fmoc-L-Dap(N3)-OH
CAS Number
684270-46-0
Purity
≥ 94% (Assay by titration)
Molecular Formula
C18H16N4O4
Molecular Weight
352.3
MDL Number
MFCD11052919
PubChem ID
71439801
Melting Point
117 - 130 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -8 to -11 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
2-(S)-Fmoc-amino-3-azidopropanoic acid, Fmoc-L-Dap(N3)-OH
CAS Number
684270-46-0
Purity
≥ 94% (Assay by titration)
Molecular Formula
C18H16N4O4
Molecular Weight
352.3
MDL Number
MFCD11052919
PubChem ID
71439801
Melting Point
117 - 130 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -8 to -11 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nb-Azido-L-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development.
  • Bioconjugation: Its azido group enables selective labeling and conjugation with biomolecules, facilitating studies in targeted drug delivery and imaging.
  • Protein Engineering: Used in the modification of proteins, it helps in creating novel protein variants with enhanced properties for therapeutic applications.
  • Research in Neuroscience: The compound can be utilized to study neuropeptides, contributing to advancements in understanding neurological disorders.
  • Material Science: It can be incorporated into polymer matrices for developing smart materials with specific functionalities, such as drug release systems.

Citations