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Catalog Number:
02436
CAS Number:
71989-28-1
Fmoc-L-methionine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Met-OH
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Product Information

Fmoc-L-methionine is a versatile amino acid derivative widely utilized in peptide synthesis and research applications. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for creating complex peptides and proteins. Its unique structure not only enhances stability but also improves solubility in organic solvents, facilitating smoother reactions and higher yields in laboratory settings. Researchers often leverage Fmoc-L-methionine in the development of pharmaceuticals, particularly in the design of peptide-based drugs and therapeutic agents, due to its ability to mimic natural amino acids while providing additional functional benefits.

In addition to its applications in peptide synthesis, Fmoc-L-methionine is also valuable in the study of protein interactions and enzyme activity, contributing to advancements in biochemistry and molecular biology. Its role in the synthesis of modified peptides allows for the exploration of new therapeutic avenues, making it a crucial component for researchers aiming to innovate in drug development. With its favorable properties and broad applicability, Fmoc-L-methionine stands out as a key reagent for professionals in the chemical and pharmaceutical industries.

Synonyms
Fmoc-L-Met-OH
CAS Number
71989-28-1
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4S
Molecular Weight
371.5
MDL Number
MFCD00037134
PubChem ID
100104
Melting Point
115 - 142 ºC
Appearance
White or off-white crystalline powder
Optical Rotation
[a]D20 = -30 to -22 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Met-OH
CAS Number
71989-28-1
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4S
Molecular Weight
371.5
MDL Number
MFCD00037134
PubChem ID
100104
Melting Point
115 - 142 ºC
Appearance
White or off-white crystalline powder
Optical Rotation
[a]D20 = -30 to -22 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-methionine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Protein Engineering: It is used in the modification of proteins, enabling scientists to study protein structure and function, which is crucial in fields like biotechnology and pharmaceuticals.
  • Drug Discovery: Fmoc-L-methionine plays a role in the development of new therapeutic agents, particularly in targeting diseases where methionine metabolism is disrupted.
  • Bioconjugation: This chemical is employed in bioconjugation processes, facilitating the attachment of biomolecules to drugs or imaging agents, enhancing their efficacy and specificity.
  • Research on Amino Acid Metabolism: It aids in studies related to amino acid metabolism, providing insights into metabolic disorders and potential therapeutic interventions.

Citations