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Catalog Number:
00672
CAS Number:
15761-39-4
Boc-L-proline
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Pro-OH, (S)-Boc-pyrrolidine-2-carboxylic acid
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$20.20 /5G
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Product Information

Boc-L-proline is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for various applications in organic chemistry. Researchers appreciate Boc-L-proline for its role in the synthesis of cyclic peptides and as a building block in the development of bioactive compounds. Its unique structure allows for the introduction of proline into peptides, which can significantly influence the conformation and biological activity of the resulting molecules.

In addition to its applications in peptide synthesis, Boc-L-proline is also employed in the development of drug candidates and in studies related to protein folding and stability. Its ability to serve as a chiral auxiliary further expands its utility in asymmetric synthesis, providing researchers with a reliable tool for creating complex molecular architectures. With its favorable properties and broad applicability, Boc-L-proline stands out as a valuable asset for chemists and researchers aiming to innovate in the fields of medicinal chemistry and biochemistry.

Synonyms
Boc-L-Pro-OH, (S)-Boc-pyrrolidine-2-carboxylic acid
CAS Number
15761-39-4
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17NO4
Molecular Weight
215.3
MDL Number
MFCD00037324
PubChem ID
268472
Melting Point
130 - 138 °C
Appearance
White to off-white powder or crystalline powder
Optical Rotation
[a]D20 = -60 ± 4 º (C=1 in AcOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Pro-OH, (S)-Boc-pyrrolidine-2-carboxylic acid
CAS Number
15761-39-4
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17NO4
Molecular Weight
215.3
MDL Number
MFCD00037324
PubChem ID
268472
Melting Point
130 - 138 °C
Appearance
White to off-white powder or crystalline powder
Optical Rotation
[a]D20 = -60 ± 4 º (C=1 in AcOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during the synthesis of peptides, allowing for the selective modification of specific sites without interfering with others.
  • Drug Development: Its structural properties make it valuable in designing proline-based pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Bioconjugation: Boc-L-proline can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies.
  • Protein Engineering: Researchers utilize this compound to introduce proline residues into proteins, enhancing their stability and functionality, especially in therapeutic applications.
  • Material Science: It is also explored in the development of new materials, particularly in creating polymers with specific mechanical properties, benefiting industries like packaging and construction.

Citations