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Catalog Number:
00494
CAS Number:
71989-14-5
Fmoc-L-aspartic acid β-tert-butyl ester
Purity:
≥ 99.7% (Chiral HPLC)
Synonym(s):
Fmoc-L-Asp(OtBu)-OH
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Product Information

Fmoc-L-aspartic acid b-tert-butyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis. Its b-tert-butyl ester functionality enhances solubility and stability, making it an ideal choice for researchers looking to streamline their synthesis processes.

In addition to its role in peptide synthesis, Fmoc-L-aspartic acid b-tert-butyl ester is also valuable in the development of pharmaceuticals and bioconjugates. Its unique structure allows for the incorporation of aspartic acid into peptides, which can be crucial for developing therapeutics targeting specific biological pathways. Researchers appreciate its ease of use and compatibility with various coupling reagents, ensuring efficient and reliable synthesis outcomes. This compound stands out for its ability to enhance the yield and purity of synthesized peptides, making it a preferred choice in both academic and industrial settings.

Synonyms
Fmoc-L-Asp(OtBu)-OH
CAS Number
71989-14-5
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C23H25NO6
Molecular Weight
411.5
MDL Number
MFCD00037131
PubChem ID
3085669
Melting Point
145 - 160 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -24 ± 2.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp(OtBu)-OH
CAS Number
71989-14-5
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C23H25NO6
Molecular Weight
411.5
MDL Number
MFCD00037131
PubChem ID
3085669
Melting Point
145 - 160 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -24 ± 2.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid b-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex proteins for various studies.
  • Drug Development: It plays a crucial role in the development of pharmaceuticals, particularly in designing drugs that target specific biological pathways.
  • Biotechnology: Used in the production of biopharmaceuticals, it helps in the formulation of therapeutic proteins, enhancing their stability and efficacy.
  • Material Science: Its properties are leveraged in creating novel materials, including hydrogels and drug delivery systems, which are essential for advanced medical applications.
  • Research in Neuroscience: This compound aids in the synthesis of neurotransmitter analogs, facilitating studies on brain function and neuropharmacology.

Citations