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Catalog Number:
07062
CAS Number:
201335-92-4
Fmoc-O-dimethylphospho-D-tyrosine
Purity:
98+%
Synonym(s):
Fmoc-D-Tyr(PO3Me2)-OH
Documents
$565.05 /1G
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Product Information

Fmoc-O-dimethylphospho-D-tyrosine is a versatile phosphotyrosine derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound features a unique Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its dimethylphosphoryl group enhances the stability and reactivity of the tyrosine residue, allowing for the exploration of phosphorylation effects in various biological systems.

Researchers utilize Fmoc-O-dimethylphospho-D-tyrosine to study signal transduction pathways and protein interactions, as well as to develop phosphopeptide-based therapeutics. Its ability to mimic natural phosphotyrosine residues makes it invaluable in the design of peptide libraries for drug discovery and development. With its excellent solubility and compatibility with various coupling reagents, this compound stands out for its efficiency in synthesizing complex peptides, thereby accelerating research and innovation in peptide chemistry.

Synonyms
Fmoc-D-Tyr(PO3Me2)-OH
CAS Number
201335-92-4
Purity
98+%
Molecular Formula
C26H26NO8P
Molecular Weight
511.47
PubChem ID
4377952
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Tyr(PO3Me2)-OH
CAS Number
201335-92-4
Purity
98+%
Molecular Formula
C26H26NO8P
Molecular Weight
511.47
PubChem ID
4377952
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-dimethylphospho-D-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of phosphopeptides, which are important for studying protein interactions and signaling pathways.
  • Drug Development: Its role in modifying amino acids allows researchers to create more effective therapeutic agents, particularly in targeting diseases related to cell signaling.
  • Bioconjugation: The compound is used in the conjugation of biomolecules, enhancing the specificity and efficacy of drug delivery systems in cancer therapy.
  • Analytical Chemistry: It aids in the development of analytical methods for detecting phosphorylated proteins, which are critical in understanding various biological processes.
  • Biotechnology: The versatility of this compound supports advancements in biotechnology, particularly in the development of biosensors that detect specific biomolecules.

Citations