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Catalog Number:
04029
CAS Number:
13512-59-9
Boc-O-benzyl-L-tyrosine 4-nitrophenyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Tyr(Bzl)-ONp
Documents
$18.53 /1G
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Product Information

Boc-O-benzyl-L-tyrosine 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features a protective Boc (tert-butyloxycarbonyl) group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its unique structure, characterized by the presence of a 4-nitrophenyl ester, enhances its reactivity, making it an excellent choice for coupling reactions. Researchers and industry professionals can leverage this compound for the development of bioactive peptides, which have applications in drug discovery and development, particularly in the fields of oncology and neurology.

The compound's ability to facilitate the formation of peptide bonds while maintaining stability under various reaction conditions makes it a preferred choice for synthetic chemists. Its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis further underscore its importance in the pharmaceutical industry. By incorporating Boc-O-benzyl-L-tyrosine 4-nitrophenyl ester into their workflows, researchers can streamline their synthesis processes, improve yields, and enhance the overall efficiency of their peptide-based projects.

Synonyms
Boc-L-Tyr(Bzl)-ONp
CAS Number
13512-59-9
Purity
≥ 99% (HPLC)
Molecular Formula
C27H28N2O7
Molecular Weight
492.53
MDL Number
MFCD00024658
PubChem ID
4411586
Melting Point
130 - 134 °C
Optical Rotation
[a]20D = 4 ± 1 º (C=1.1 in THF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Tyr(Bzl)-ONp
CAS Number
13512-59-9
Purity
≥ 99% (HPLC)
Molecular Formula
C27H28N2O7
Molecular Weight
492.53
MDL Number
MFCD00024658
PubChem ID
4411586
Melting Point
130 - 134 °C
Optical Rotation
[a]20D = 4 ± 1 º (C=1.1 in THF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-benzyl-L-tyrosine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of biologically active compounds. Its protective groups facilitate selective reactions, making it easier to create complex structures.
  • Drug Development: In pharmaceutical research, it is used to create prodrugs that enhance the solubility and bioavailability of therapeutic agents. This can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is employed in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents. This application is crucial in targeted drug delivery systems.
  • Fluorescent Labeling: It can be used to introduce fluorescent tags in molecular biology studies, aiding in the visualization of proteins and other biomolecules in live cells.
  • Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is explored in studies related to neuropharmacology, helping to understand receptor interactions and signaling pathways.

Citations