Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
03939
CAS Number:
127633-36-7
Fmoc-O-dimethylphospho-L-tyrosine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Tyr(PO3Me2)-OH
Documents
$181.67 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-O-dimethylphospho-L-tyrosine is a versatile phosphotyrosine derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound is particularly valuable in the field of medicinal chemistry and biochemistry, where it is utilized for the development of phosphopeptide-based drugs and research tools. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective deprotection under mild conditions, making it an ideal choice for synthesizing complex peptides that require precise control over functional groups.

Researchers appreciate Fmoc-O-dimethylphospho-L-tyrosine for its ability to mimic natural phosphotyrosine residues, facilitating studies on protein interactions and signaling pathways. This compound has been effectively employed in the synthesis of phosphopeptides that can be used to probe the activity of kinases and phosphatases, thereby advancing our understanding of cellular processes. Its stability and compatibility with various coupling reagents further enhance its utility in peptide synthesis, making it a preferred choice for professionals in pharmaceutical and academic research settings.

Synonyms
Fmoc-L-Tyr(PO3Me2)-OH
CAS Number
127633-36-7
Purity
≥ 98% (HPLC)
Molecular Formula
C26H26NO8P
Molecular Weight
511.47
MDL Number
MFCD00133599
PubChem ID
4377952
Melting Point
97 - 105 ºC
Appearance
White product
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tyr(PO3Me2)-OH
CAS Number
127633-36-7
Purity
≥ 98% (HPLC)
Molecular Formula
C26H26NO8P
Molecular Weight
511.47
MDL Number
MFCD00133599
PubChem ID
4377952
Melting Point
97 - 105 ºC
Appearance
White product
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-dimethylphospho-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of phosphotyrosine-containing peptides, which are important for studying protein interactions and signaling pathways.
  • Drug Development: It is used in the development of pharmaceuticals targeting tyrosine kinases, which play a significant role in cancer and other diseases, providing a pathway for innovative treatments.
  • Bioconjugation: The chemical is employed in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, enhancing the effectiveness of drug delivery systems.
  • Analytical Chemistry: It aids in the development of analytical methods for detecting and quantifying phosphotyrosine in biological samples, facilitating research in cellular signaling and disease mechanisms.
  • Biotechnology: This compound is utilized in various biotechnological applications, such as the design of biosensors that can detect specific proteins or enzymes, improving diagnostic capabilities.

Citations