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Catalog Number:
02467
CAS Number:
112402-12-7
Fmoc-O-2,6-dichlorobenzyl-L-tyrosine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Tyr(2,6-diCl-Bzl)-OH
Documents
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Product Information

Fmoc-O-2,6-dichlorobenzyl-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its structure, characterized by the presence of a 2,6-dichlorobenzyl moiety, enhances the compound's stability and reactivity, making it an excellent choice for researchers focused on developing complex peptides and biologically active compounds.

In the pharmaceutical industry, Fmoc-O-2,6-dichlorobenzyl-L-tyrosine is particularly valuable for synthesizing peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its unique properties allow for improved yields and purities in peptide synthesis, which can significantly accelerate the drug discovery process. Additionally, this compound's compatibility with various coupling reagents and solvents makes it a preferred choice for researchers looking to optimize their synthetic pathways.

Synonyms
Fmoc-L-Tyr(2,6-diCl-Bzl)-OH
CAS Number
112402-12-7
Purity
≥ 98% (HPLC)
Molecular Formula
C31H25NO5Cl2
Molecular Weight
562.5
MDL Number
MFCD00065685
Melting Point
162-176 ºC
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Tyr(2,6-diCl-Bzl)-OH
CAS Number
112402-12-7
Purity
≥ 98% (HPLC)
Molecular Formula
C31H25NO5Cl2
Molecular Weight
562.5
MDL Number
MFCD00065685
Melting Point
162-176 ºC
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-2,6-dichlorobenzyl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, especially in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry, particularly in the design of peptide-based drugs, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, enhancing their targeting capabilities and efficacy.
  • Research in Neuroscience: It is utilized in studies related to neurotransmitter pathways, contributing to the understanding of neurological disorders and the development of potential therapies.
  • Protein Engineering: Fmoc-O-2,6-dichlorobenzyl-L-tyrosine is valuable in protein engineering, allowing researchers to modify proteins for improved stability and functionality in various applications.

Citations