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Catalog Number:
03892
CAS Number:
50305-28-7
Nα-Z-L-tryptophan N-hydroxysuccinimide ester
Purity:
≥ 98% (Assay)
Synonym(s):
Z-L-Trp-OSu
Documents
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Product Information

Na-Z-L-tryptophan N-hydroxysuccinimide ester is a versatile compound that plays a significant role in biochemical research and pharmaceutical applications. This ester derivative of tryptophan is particularly valuable for its ability to facilitate peptide synthesis and modification, making it an essential tool for researchers involved in drug development and protein engineering. Its unique structure enhances solubility and stability, which are critical factors in biochemical assays and therapeutic formulations.

In practical applications, Na-Z-L-tryptophan N-hydroxysuccinimide ester is utilized in the synthesis of bioactive peptides and as a building block in the development of novel therapeutics targeting various biological pathways. Its compatibility with various coupling reactions allows for efficient incorporation into larger peptide sequences, thus streamlining the process of peptide synthesis. Researchers appreciate its ease of use and effectiveness in enhancing the bioavailability of peptide-based drugs, making it a preferred choice in both academic and industrial settings.

Synonyms
Z-L-Trp-OSu
CAS Number
50305-28-7
Purity
≥ 98% (Assay)
Molecular Formula
C23H21N3O6
Molecular Weight
435.44
MDL Number
MFCD00153347
PubChem ID
13819930
Appearance
White to cream powder
Optical Rotation
[a]D = -60 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-L-Trp-OSu
CAS Number
50305-28-7
Purity
≥ 98% (Assay)
Molecular Formula
C23H21N3O6
Molecular Weight
435.44
MDL Number
MFCD00153347
PubChem ID
13819930
Appearance
White to cream powder
Optical Rotation
[a]D = -60 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Z-L-tryptophan N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an effective building block in the synthesis of peptides, particularly those that require tryptophan residues. Its unique structure allows for selective coupling reactions, enhancing the efficiency of peptide formation.
  • Drug Development: In pharmaceutical research, it is employed to create novel drug candidates, especially in the development of therapeutics targeting neurological disorders, due to tryptophan's role in serotonin production.
  • Bioconjugation: The ester functionality makes it suitable for bioconjugation applications, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in the development of targeted drug delivery systems.
  • Fluorescent Probes: It can be modified to create fluorescent probes for imaging studies, aiding researchers in visualizing biological processes in real-time, which is vital for understanding cellular mechanisms.
  • Protein Labeling: This compound is also used in the labeling of proteins for various analytical techniques, such as mass spectrometry and chromatography, providing insights into protein interactions and functions.

Citations