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Catalog Number:
03753
CAS Number:
84771-20-0
Nα-Fmoc-L-tryptophan N-hydroxysuccinimide ester
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Trp-OSu
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Product Information

Na-Fmoc-L-tryptophan N-hydroxysuccinimide ester is a versatile and valuable compound widely utilized in peptide synthesis and drug development. This derivative of tryptophan features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers aiming to create complex peptides with high purity and yield. The N-hydroxysuccinimide ester functionality enhances the reactivity of the compound, facilitating the formation of amide bonds with nucleophiles, which is crucial in the development of peptide-based therapeutics and bioconjugates.

In addition to its applications in peptide synthesis, Na-Fmoc-L-tryptophan N-hydroxysuccinimide ester is also employed in the study of protein interactions and the design of novel biomaterials. Its ability to form stable conjugates with various biomolecules opens up new avenues for research in drug delivery systems and targeted therapies. Researchers and industry professionals can leverage this compound's properties to streamline their synthesis processes and enhance the efficacy of their products, making it a valuable addition to any laboratory focused on peptide chemistry and bioconjugation.

Synonyms
Fmoc-L-Trp-OSu
CAS Number
84771-20-0
Purity
≥ 97% (HPLC)
Molecular Formula
C30H25N3O6
Molecular Weight
523.5
MDL Number
MFCD00235836
PubChem ID
74765177
Melting Point
157-162 ºC
Appearance
White powder
Optical Rotation
[a]D20
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Trp-OSu
CAS Number
84771-20-0
Purity
≥ 97% (HPLC)
Molecular Formula
C30H25N3O6
Molecular Weight
523.5
MDL Number
MFCD00235836
PubChem ID
74765177
Melting Point
157-162 ºC
Appearance
White powder
Optical Rotation
[a]D20
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-L-tryptophan N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enabling researchers to create complex molecules for drug development.
  • Bioconjugation: It is used to attach biomolecules to surfaces or other molecules, enhancing the effectiveness of therapeutic agents in targeted drug delivery systems.
  • Protein Labeling: The ester form allows for selective labeling of proteins, which is crucial in studying protein interactions and functions in various biological systems.
  • Research in Neuroscience: By facilitating the study of tryptophan derivatives, it aids in understanding neurotransmitter pathways and their implications in mental health.
  • Pharmaceutical Development: Its unique properties make it beneficial in developing new pharmaceuticals, particularly those targeting neurological and psychiatric disorders.

Citations