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Catalog Number:
01954
CAS Number:
143824-78-6
Nα-Fmoc-Nin-Boc-L-tryptophan
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Trp(Boc)-OH
Documents
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Product Information

Na-Fmoc-Nin-Boc-L-tryptophan is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features protective groups that enhance its stability and reactivity, making it an ideal choice for researchers focused on synthesizing complex peptides. Its unique structure allows for selective reactions, facilitating the incorporation of tryptophan into various peptide sequences, which is crucial in the design of bioactive compounds and pharmaceuticals.

In addition to its applications in synthetic chemistry, Na-Fmoc-Nin-Boc-L-tryptophan is also valuable in the study of protein interactions and structure-function relationships. Researchers can leverage its properties to explore the role of tryptophan in biological systems, potentially leading to advancements in therapeutic strategies targeting neurological disorders and cancer. The compound's ability to provide controlled release of the amino acid during synthesis further enhances its appeal, allowing for precise manipulation in various experimental setups.

Synonyms
Fmoc-L-Trp(Boc)-OH
CAS Number
143824-78-6
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C31H30N2O6
Molecular Weight
526.6
MDL Number
MFCD00153366
PubChem ID
4405989
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 4 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Trp(Boc)-OH
CAS Number
143824-78-6
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C31H30N2O6
Molecular Weight
526.6
MDL Number
MFCD00153366
PubChem ID
4405989
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 4 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nin-Boc-L-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.
  • Drug Development: It plays a significant role in pharmaceutical research, particularly in the development of peptide-based drugs, which can offer targeted therapeutic effects with fewer side effects compared to traditional small molecules.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of peptides to other biomolecules, such as antibodies or nanoparticles, enhancing drug delivery systems.
  • Research in Neuroscience: It is valuable in studies related to neurotransmitter pathways, particularly due to tryptophan's role as a precursor to serotonin, aiding in the understanding of mood disorders.
  • Protein Engineering: This chemical is instrumental in the design of modified proteins, allowing researchers to explore structure-function relationships and develop proteins with enhanced stability or activity.

Citations