Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
35196
CAS Number:
73724-46-6
Fmoc-L-serine benzyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Ser-Obzl, (S)-Fmoc-2-amino-3-hydroxypropionic acid benzyl ester
Documents
$30.00 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-serine benzyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of medicinal chemistry and biochemistry. Its benzyl ester functionality enhances solubility and stability, facilitating its use in various organic reactions.

Researchers and industry professionals appreciate Fmoc-L-serine benzyl ester for its role in the development of therapeutic peptides and proteins, particularly in drug discovery and development. Its unique properties enable the formation of complex peptide structures, which are crucial for studying protein interactions and functions. Additionally, the compound's compatibility with automated synthesizers streamlines the peptide synthesis process, making it an ideal choice for laboratories focused on high-throughput screening and synthesis.

Synonyms
Fmoc-L-Ser-Obzl, (S)-Fmoc-2-amino-3-hydroxypropionic acid benzyl ester
CAS Number
73724-46-6
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.5
MDL Number
MFCD09752867
PubChem ID
12930237
Melting Point
92 - 102 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -12 ± 2 º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Ser-Obzl, (S)-Fmoc-2-amino-3-hydroxypropionic acid benzyl ester
CAS Number
73724-46-6
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.5
MDL Number
MFCD09752867
PubChem ID
12930237
Melting Point
92 - 102 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -12 ± 2 º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-serine benzyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: In pharmaceutical research, it is used to create modified amino acids that can lead to novel therapeutic agents. Its ability to easily undergo further modifications makes it valuable in drug design.
  • Bioconjugation: The compound is employed in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules. This is crucial in developing targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Fmoc-L-serine benzyl ester is used in studies involving neurotransmitter systems, aiding in the exploration of neurological pathways and potential treatments for neurodegenerative diseases.
  • Protein Engineering: It plays a role in the engineering of proteins with enhanced properties, such as stability and activity. This is particularly important in biotechnology applications where modified proteins are needed for industrial processes.

Citations