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Catalog Number:
35188
CAS Number:
159610-93-2
Fmoc-O-methyl-L-serine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Ser(Me)-OH, Fmoc-(S)-2-Amino-3-methoxypropionic acid
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$95.60 /1G
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Product Information

Fmoc-O-methyl-L-serine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its unique methoxy group enhances solubility and stability, facilitating its incorporation into various peptide sequences.

Researchers have leveraged Fmoc-O-methyl-L-serine in the development of therapeutic peptides, particularly those targeting neurological disorders and cancer. Its ability to provide structural diversity in peptide libraries makes it a valuable tool for drug discovery and optimization. Additionally, the compound's favorable reactivity profile allows for straightforward coupling reactions, streamlining the synthesis process. With its proven applications and benefits, Fmoc-O-methyl-L-serine stands out as a crucial component in advancing peptide-based therapeutics.

Synonyms
Fmoc-L-Ser(Me)-OH, Fmoc-(S)-2-Amino-3-methoxypropionic acid
CAS Number
159610-93-2
Purity
≥ 99% (HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.36
MDL Number
MFCD02682604
PubChem ID
19048665
Melting Point
140 - 150 °C
Appearance
White powder
Optical Rotation
[a]20D = - 9.5 ± 1° (C=2 in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Ser(Me)-OH, Fmoc-(S)-2-Amino-3-methoxypropionic acid
CAS Number
159610-93-2
Purity
≥ 99% (HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.36
MDL Number
MFCD02682604
PubChem ID
19048665
Melting Point
140 - 150 °C
Appearance
White powder
Optical Rotation
[a]20D = - 9.5 ± 1° (C=2 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-methyl-L-serine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, allowing for the introduction of specific functional groups that enhance the properties of the resulting peptides.
  • Drug Development: In pharmaceutical research, it is used to create modified amino acids that can improve the efficacy and stability of drug candidates, particularly in the development of peptide-based therapeutics.
  • Bioconjugation: Fmoc-O-methyl-L-serine is employed in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Protein Engineering: This compound aids in the design of proteins with enhanced properties, such as increased stability or altered activity, which is valuable in various biotechnological applications.
  • Research in Neuroscience: It is used in studies related to neurotransmitter systems, providing insights into neurological functions and potential therapeutic targets for neurological disorders.

Citations