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Catalog Number:
05706
CAS Number:
122889-11-6
Fmoc-O-benzyl-D-serine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Ser(Bzl)-OH
Documents
$22.03 /1G
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Product Information

Fmoc-O-benzyl-D-serine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is crucial for the selective deprotection of amino acids during solid-phase peptide synthesis. Its benzyl ether moiety enhances solubility and stability, making it an excellent choice for researchers focused on synthesizing complex peptides or studying protein interactions.

In the pharmaceutical industry, Fmoc-O-benzyl-D-serine serves as a building block for bioactive peptides, contributing to the development of therapeutics targeting various diseases. Its unique structure allows for the introduction of functional groups that can modify biological activity, thus expanding its application in medicinal chemistry. Researchers appreciate its compatibility with various coupling reagents and its ability to facilitate the synthesis of cyclic peptides, which are often more stable and effective than their linear counterparts.

Synonyms
Fmoc-D-Ser(Bzl)-OH
CAS Number
122889-11-6
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.5
MDL Number
MFCD00237032
PubChem ID
4386775
Melting Point
123-147 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -23 ± 2º (C=1 in EtOAc)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Ser(Bzl)-OH
CAS Number
122889-11-6
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.5
MDL Number
MFCD00237032
PubChem ID
4386775
Melting Point
123-147 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -23 ± 2º (C=1 in EtOAc)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-benzyl-D-serine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing researchers to selectively modify amino acids without affecting others. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its application in drug design helps in creating more effective therapeutic agents by modifying the structure of bioactive peptides, enhancing their stability and bioavailability.
  • Bioconjugation: Fmoc-O-benzyl-D-serine is used in bioconjugation techniques, where it aids in attaching biomolecules to surfaces or other molecules, which is essential in developing targeted drug delivery systems.
  • Research in Neuroscience: This compound is involved in studies related to neurotransmitter systems, helping researchers understand the role of peptides in brain function and potential treatments for neurological disorders.
  • Custom Synthesis: It allows for the custom synthesis of modified amino acids, catering to specific research needs in various fields, including materials science and biotechnology.

Citations