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Catalog Number:
04918
CAS Number:
93204-36-5
Z-D-serine methyl ester
Purity:
≥ 97% (HPLC)
Synonym(s):
Z-D-Ser-OMe, Z-D-β-hydroxyalanine methyl ester, (R-Z-2-amino-3-hydroxypropionic acid methyl ester
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Product Information

Z-D-serine methyl ester is a valuable compound widely utilized in biochemical research and pharmaceutical applications. This amino acid derivative serves as a crucial building block in the synthesis of various bioactive molecules, particularly in the development of neuroactive drugs. Its unique structure, featuring a hydroxyl group and a phenylmethoxycarbonyl group, enhances its solubility and stability, making it an ideal candidate for studies related to neurotransmission and neuropharmacology. Researchers have leveraged Z-D-serine methyl ester in the exploration of therapeutic agents for conditions such as schizophrenia and other neurodegenerative disorders, where modulation of glutamatergic signaling is essential.

In addition to its applications in drug development, Z-D-serine methyl ester is also employed in peptide synthesis and as a chiral auxiliary in asymmetric synthesis, providing significant advantages over similar compounds due to its high purity and ease of use. Its role in enhancing the efficacy of therapeutic compounds makes it a sought-after reagent in both academic and industrial settings. With its diverse applications and potential for innovation, Z-D-serine methyl ester continues to be a key player in advancing research and development in the life sciences.

Synonyms
Z-D-Ser-OMe, Z-D-β-hydroxyalanine methyl ester, (R-Z-2-amino-3-hydroxypropionic acid methyl ester
CAS Number
93204-36-5
Purity
≥ 97% (HPLC)
Molecular Formula
C12H15NO5
Molecular Weight
253.2
MDL Number
MFCD00799501
PubChem ID
323417
Melting Point
28-34 °C
Appearance
White powder
Optical Rotation
[a]D20 = +14 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Z-D-Ser-OMe, Z-D-β-hydroxyalanine methyl ester, (R-Z-2-amino-3-hydroxypropionic acid methyl ester
CAS Number
93204-36-5
Purity
≥ 97% (HPLC)
Molecular Formula
C12H15NO5
Molecular Weight
253.2
MDL Number
MFCD00799501
PubChem ID
323417
Melting Point
28-34 °C
Appearance
White powder
Optical Rotation
[a]D20 = +14 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-D-serine methyl ester is widely utilized in research focused on

  • Neuroscience: This compound serves as a valuable tool in studying neurotransmitter systems, particularly in understanding the role of D-serine in synaptic transmission and neurodevelopment.
  • Pharmaceutical Development: It is used in the synthesis of potential therapeutic agents targeting neurological disorders, offering a pathway for developing treatments for conditions like schizophrenia.
  • Biochemical Research: Researchers employ Z-D-serine methyl ester to investigate its effects on enzyme activity and protein interactions, contributing to the understanding of metabolic pathways.
  • Drug Formulation: Its properties make it suitable for creating formulations that enhance the bioavailability of drugs, improving their efficacy in clinical applications.
  • Analytical Chemistry: The compound is utilized in various analytical techniques, including chromatography, to identify and quantify amino acids in complex mixtures.

Citations