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Catalog Number:
03925
CAS Number:
82911-78-2
Fmoc-L-serine methyl ester
Purity:
≥ 99.5% (HPLC)
Synonym(s):
Fmoc-L-Ser-OMe, Fmoc-L-β-hydroxyalanine methyl ester, (S-Fmoc-2-Amino-3-hydroxypropionic acid methyl ester
Documents
$72.31 /250MG
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Product Information

Fmoc-L-serine methyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features the Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for easy deprotection under mild conditions, making it an ideal choice for researchers looking to streamline their synthesis processes.

In addition to its role in peptide synthesis, Fmoc-L-serine methyl ester is also valuable in the development of pharmaceuticals and biologically active compounds. Its hydroxyl group enhances solubility and reactivity, which can be advantageous in drug formulation and delivery systems. Researchers in medicinal chemistry and biochemistry will find this compound particularly useful for creating complex molecules with specific biological activities. With its favorable properties and applications, Fmoc-L-serine methyl ester stands out as a crucial building block in modern chemical research and development.

Synonyms
Fmoc-L-Ser-OMe, Fmoc-L-β-hydroxyalanine methyl ester, (S-Fmoc-2-Amino-3-hydroxypropionic acid methyl ester
CAS Number
82911-78-2
Purity
≥ 99.5% (HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.3
MDL Number
MFCD00672334
PubChem ID
22117523
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -12 ± 2º (C=1, DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Ser-OMe, Fmoc-L-β-hydroxyalanine methyl ester, (S-Fmoc-2-Amino-3-hydroxypropionic acid methyl ester
CAS Number
82911-78-2
Purity
≥ 99.5% (HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.3
MDL Number
MFCD00672334
PubChem ID
22117523
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -12 ± 2º (C=1, DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-serine methyl ester is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studies in biochemistry and molecular biology.
  • Drug Development: Its role in modifying amino acids makes it valuable in the pharmaceutical industry for developing new drugs, particularly those targeting neurological disorders.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of biomolecules to various surfaces, which is crucial in creating targeted drug delivery systems.
  • Protein Engineering: Researchers utilize it to introduce modifications in proteins, enhancing their stability and function, which is essential in the development of biotherapeutics.
  • Analytical Chemistry: It is employed in analytical methods to study protein interactions, providing insights that are vital for understanding biological processes.

Citations