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Catalog Number:
03734
CAS Number:
158171-14-3 
Fmoc-O-benzylphospho-L-serine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Ser(HPO3Bzl)-OH
Documents
$79.22 /250MG
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Product Information

Fmoc-O-benzylphospho-L-serine is a versatile phosphoamino acid derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound is particularly valuable in the field of medicinal chemistry and biochemistry, where it serves as a key building block for the development of phosphopeptides. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective deprotection under mild conditions, making it an ideal choice for researchers looking to incorporate phosphoserine residues into peptides without compromising their integrity.

In addition to its utility in peptide synthesis, Fmoc-O-benzylphospho-L-serine is also employed in the study of protein phosphorylation and signaling pathways, providing insights into cellular mechanisms and potential therapeutic targets. Its compatibility with various coupling reagents and solid-phase synthesis techniques further enhances its appeal for researchers aiming to create complex peptide libraries. With its ability to facilitate the exploration of phosphoproteins and their biological functions, this compound stands out as a valuable asset in both academic and industrial research settings.

Synonyms
Fmoc-L-Ser(HPO3Bzl)-OH
CAS Number
158171-14-3 
Purity
≥ 97% (HPLC)
Molecular Formula
C25H24NO8P
Molecular Weight
497.4
MDL Number
MFCD00797869
PubChem ID
3373865
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-L-Ser(HPO3Bzl)-OH
CAS Number
158171-14-3 
Purity
≥ 97% (HPLC)
Molecular Formula
C25H24NO8P
Molecular Weight
497.4
MDL Number
MFCD00797869
PubChem ID
3373865
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-benzylphospho-L-serine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of phosphopeptides, which are important for studying protein interactions and signaling pathways.
  • Drug Development: It plays a crucial role in the development of therapeutic agents that target phosphorylation processes, making it valuable in pharmaceutical research.
  • Bioconjugation: Researchers use it to create bioconjugates for targeted drug delivery systems, enhancing the efficacy of treatments while minimizing side effects.
  • Analytical Chemistry: This chemical is employed in various analytical techniques to detect and quantify phosphoserine in biological samples, aiding in biomarker discovery.
  • Biotechnology: It is utilized in the production of modified proteins for biotechnological applications, such as enzyme engineering and vaccine development.

Citations