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Catalog Number:
02453
CAS Number:
83792-48-7
Fmoc-O-benzyl-L-serine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Ser(Bzl)-OH
Documents
$22.03 /1G
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Product Information

Fmoc-O-benzyl-L-serine is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, facilitating the incorporation of serine into complex structures. Its benzyl group enhances solubility and stability, making it an ideal choice for researchers focused on developing bioactive peptides and pharmaceuticals.

This compound is particularly valuable in the production of peptide-based therapeutics, where precise amino acid sequences are crucial for biological activity. Fmoc-O-benzyl-L-serine has been employed in various applications, including drug discovery, protein engineering, and the development of enzyme inhibitors. Its unique properties not only streamline the synthesis process but also improve the overall yield and purity of the final products, making it a preferred choice among professionals in the field.

Synonyms
Fmoc-L-Ser(Bzl)-OH
CAS Number
83792-48-7
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.5
MDL Number
MFCD00065674
Melting Point
140 - 150 °C
Appearance
White powder
Optical Rotation
[a]20D = 24 ± 2 º (C=1 in Ethyl acetate)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Ser(Bzl)-OH
CAS Number
83792-48-7
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.5
MDL Number
MFCD00065674
Melting Point
140 - 150 °C
Appearance
White powder
Optical Rotation
[a]20D = 24 ± 2 º (C=1 in Ethyl acetate)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-benzyl-L-serine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective groups facilitate the sequential addition of amino acids, leading to high-purity peptide products.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. Its unique structure allows for the development of compounds with enhanced stability and bioactivity, making it valuable in therapeutic applications.
  • Bioconjugation: Fmoc-O-benzyl-L-serine can be employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This is particularly useful in creating targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: Researchers utilize this compound to modify proteins, enhancing their properties such as solubility and stability. This is crucial in developing proteins for industrial applications, including enzymes and antibodies.
  • Research in Neuroscience: Its application in synthesizing neuropeptides allows for the exploration of neurological pathways and the development of potential treatments for neurological disorders.

Citations