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Catalog Number:
06610
CAS Number:
108321-19-3
H-Pro-pNA·TFA
Purity:
≥ 99% (HPLC)
Synonym(s):
L-Proline 4-nitroanilide trifluoroacetate
Documents
$72.31 /250MG
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Product Information

H-Pro-pNA·TFA is a specialized compound known for its application in biochemical research and pharmaceutical development. This compound, also recognized as 4-nitrophenyl pyrrolidine-2-carboxamide, is particularly valued for its role as a substrate in enzyme assays, where it serves as a chromogenic indicator. Its unique structure allows for the selective detection of proteolytic activity, making it an essential tool for researchers studying enzyme kinetics and protein interactions.

In addition to its use in enzymatic studies, H-Pro-pNA·TFA is beneficial in the synthesis of peptide derivatives and can be utilized in drug discovery processes. The trifluoroacetic acid component enhances its solubility and stability in various solvents, facilitating its application in diverse experimental conditions. Researchers and industry professionals appreciate its reliability and effectiveness, particularly in high-throughput screening environments where precision is paramount. With its robust performance and versatility, H-Pro-pNA·TFA stands out as a valuable asset in both academic and industrial laboratories.

Synonyms
L-Proline 4-nitroanilide trifluoroacetate
CAS Number
108321-19-3
Purity
≥ 99% (HPLC)
Molecular Formula
C11H13N3O3·C2HO2F3
Molecular Weight
349.26
MDL Number
MFCD00069671
PubChem ID
74764858
Melting Point
150-156 ºC
Appearance
Off-white to yellow crystalline powder
Optical Rotation
[α]D20 = -32 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-Proline 4-nitroanilide trifluoroacetate
CAS Number
108321-19-3
Purity
≥ 99% (HPLC)
Molecular Formula
C11H13N3O3·C2HO2F3
Molecular Weight
349.26
MDL Number
MFCD00069671
PubChem ID
74764858
Melting Point
150-156 ºC
Appearance
Off-white to yellow crystalline powder
Optical Rotation
[α]D20 = -32 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

H-Pro-pNA·TFA is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate for various proteases, allowing researchers to measure enzyme activity and kinetics effectively.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for screening potential drug candidates, particularly in the development of protease inhibitors.
  • Biochemical Research: Used in studies involving protein interactions, it helps scientists understand the mechanisms of action for various biological processes.
  • Diagnostic Applications: The compound is beneficial in developing assays for disease markers, aiding in the early detection of certain health conditions.
  • Educational Purposes: It is often used in academic laboratories for teaching purposes, providing students with hands-on experience in biochemical techniques.

Citations