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Catalog Number:
05092
CAS Number:
115186-37-3
Boc-L-proline N,O-dimethylhydroxamide
Purity:
≥ 95% (HPLC)
Synonym(s):
Boc-L-Pro-N(OMe)Me
Documents
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Product Information

Boc-L-proline N,O-dimethylhydroxamide is a versatile compound widely utilized in the fields of organic synthesis and medicinal chemistry. This compound is recognized for its unique structure, which includes a tert-butyl protecting group that enhances its stability and reactivity. Researchers often employ Boc-L-proline N,O-dimethylhydroxamide in the synthesis of peptide and protein derivatives, making it an essential building block in the development of pharmaceuticals. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups makes it particularly valuable in drug discovery and development.

In addition to its applications in peptide synthesis, Boc-L-proline N,O-dimethylhydroxamide serves as a chiral auxiliary in asymmetric synthesis, allowing chemists to produce enantiomerically pure compounds efficiently. This characteristic is crucial in the pharmaceutical industry, where the efficacy and safety of drugs can depend on their stereochemistry. With its favorable properties and broad applicability, Boc-L-proline N,O-dimethylhydroxamide stands out as a key reagent for researchers and industry professionals seeking to innovate in chemical synthesis and drug formulation.

Synonyms
Boc-L-Pro-N(OMe)Me
CAS Number
115186-37-3
Purity
≥ 95% (HPLC)
Molecular Formula
C12H22N2O4
Molecular Weight
258.3
MDL Number
MFCD00209555
PubChem ID
3517120
Appearance
Light yellow liquid
Optical Rotation
[α]D25 = -19 ± 2º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Pro-N(OMe)Me
CAS Number
115186-37-3
Purity
≥ 95% (HPLC)
Molecular Formula
C12H22N2O4
Molecular Weight
258.3
MDL Number
MFCD00209555
PubChem ID
3517120
Appearance
Light yellow liquid
Optical Rotation
[α]D25 = -19 ± 2º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-proline N,O-dimethylhydroxamide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enhancing the efficiency of creating complex structures in pharmaceutical research.
  • Drug Development: Its unique properties allow for the development of novel drug candidates, particularly in the field of anti-cancer therapies, where it can modify the activity of bioactive compounds.
  • Bioconjugation: The compound is useful in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutic applications.
  • Research on Enzyme Inhibition: It is employed in studies aimed at understanding enzyme mechanisms, providing insights that can lead to the development of inhibitors for various diseases.
  • Material Science: The compound can be used in the formulation of advanced materials, contributing to the development of smart materials with tailored properties for specific applications.

Citations