Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
01376
CAS Number:
37784-17-1
Boc-D-proline
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-D-Pro-OH, (R)-Boc-pyrrolidine-2-carboxylic acid
Documents
$18.53 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Boc-D-proline is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers often employ Boc-D-proline in the development of bioactive peptides and as a building block in the synthesis of complex molecules. Its unique structure allows for the introduction of proline residues into peptides, which can significantly influence the conformation and biological activity of the resulting compounds.

In addition to its role in peptide synthesis, Boc-D-proline is also used in the design of inhibitors and modulators for various biological targets, including enzymes and receptors. Its ability to mimic natural amino acids while providing enhanced stability makes it a preferred choice for medicinal chemists and biochemists. With its versatile applications and essential role in the development of therapeutic agents, Boc-D-proline stands out as a crucial compound for researchers aiming to innovate in drug discovery and development.

Synonyms
Boc-D-Pro-OH, (R)-Boc-pyrrolidine-2-carboxylic acid
CAS Number
37784-17-1
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C10H17NO4
Molecular Weight
215.3
MDL Number
MFCD00063226
PubChem ID
268472
Melting Point
130 - 138 °C
Appearance
White crystal
Optical Rotation
[a]D20 = 60 ± 2 º (C=1 in AcOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Pro-OH, (R)-Boc-pyrrolidine-2-carboxylic acid
CAS Number
37784-17-1
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C10H17NO4
Molecular Weight
215.3
MDL Number
MFCD00063226
PubChem ID
268472
Melting Point
130 - 138 °C
Appearance
White crystal
Optical Rotation
[a]D20 = 60 ± 2 º (C=1 in AcOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-proline is widely utilized in research focused on:

  • Peptide Synthesis: It serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.
  • Drug Development: Researchers leverage Boc-D-proline for its ability to enhance the stability and bioavailability of drug candidates, making it a valuable component in medicinal chemistry.
  • Protein Engineering: This compound is used to modify proteins, allowing scientists to study protein folding and interactions, which is crucial for understanding diseases.
  • Chiral Resolution: Boc-D-proline is effective in separating enantiomers in chiral synthesis, aiding in the production of optically pure compounds for various applications.
  • Material Science: Its unique properties are exploited in creating novel materials, such as hydrogels, which have applications in drug delivery and tissue engineering.

Citations