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Catalog Number:
03112
CAS Number:
13505-32-3
Tosyl-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Tos-L-Phe-OH
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Product Information

Tosyl-L-phenylalanine is a versatile compound widely recognized for its applications in peptide synthesis and pharmaceutical research. This amino acid derivative, characterized by its sulfonyl group, enhances the stability and solubility of peptides, making it an invaluable tool for researchers in the development of therapeutic agents. Its unique structure allows for the introduction of various functional groups, facilitating the design of complex molecules with improved bioactivity.

In the pharmaceutical industry, Tosyl-L-phenylalanine is often utilized in the synthesis of peptide-based drugs, particularly those targeting specific receptors or pathways. Its ability to act as a protecting group during peptide synthesis allows for selective modifications, leading to the creation of more effective and targeted therapies. Additionally, its application in the development of enzyme inhibitors and other bioactive compounds highlights its significance in medicinal chemistry. Researchers and industry professionals can leverage the properties of Tosyl-L-phenylalanine to enhance their projects, streamline synthesis processes, and ultimately contribute to advancements in drug development.

Synonyms
Tos-L-Phe-OH
CAS Number
13505-32-3
Purity
≥ 98% (HPLC)
Molecular Formula
C16H17NO4S
Molecular Weight
319.4
MDL Number
MFCD00037251
PubChem ID
309599
Melting Point
162-166 ?C
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -16.7 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Tos-L-Phe-OH
CAS Number
13505-32-3
Purity
≥ 98% (HPLC)
Molecular Formula
C16H17NO4S
Molecular Weight
319.4
MDL Number
MFCD00037251
PubChem ID
309599
Melting Point
162-166 ?C
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -16.7 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tosyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: It plays a significant role in the design of new drugs, particularly in creating compounds that can interact with biological targets effectively, enhancing the efficacy of therapeutic agents.
  • Biotechnology: In the field of biotechnology, it is used to modify proteins, aiding in the production of enzymes with improved stability and activity, which can be beneficial in industrial processes.
  • Research in Neuroscience: The compound is utilized in studies related to neurotransmitter pathways, helping researchers understand the biochemical processes underlying neurological functions and disorders.
  • Analytical Chemistry: It is employed as a standard in various analytical techniques, assisting in the quantification of amino acids and related compounds in complex biological samples.

Citations