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Catalog Number:
05692
CAS Number:
200344-33-8
Fmoc-D-citrulline
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Cit-OH, (R)-2-Fmoc-amino-5-ureidopentanoic acid
Documents
$65.40 /250MG
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Product Information

Fmoc-D-citrulline is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient incorporation into peptides, making it a valuable building block in the creation of therapeutic agents, particularly in the fields of oncology and immunology. Researchers appreciate Fmoc-D-citrulline for its stability and compatibility with various coupling reagents, facilitating streamlined synthesis processes.

In addition to its role in peptide synthesis, Fmoc-D-citrulline is also being explored for its potential applications in the development of novel biomaterials and drug delivery systems. Its ability to enhance solubility and bioavailability makes it an attractive candidate for formulating new pharmaceuticals. With its proven utility in both academic and industrial settings, Fmoc-D-citrulline stands out as a critical component for researchers aiming to innovate in peptide-based therapies.

Synonyms
Fmoc-D-Cit-OH, (R)-2-Fmoc-amino-5-ureidopentanoic acid
CAS Number
200344-33-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C21H23N3O5
Molecular Weight
397.4
MDL Number
MFCD00151942
PubChem ID
4224076
Melting Point
150 - 170 °C
Appearance
White powder
Optical Rotation
[a]D20 = 9 ± 1 º (C=2 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Cit-OH, (R)-2-Fmoc-amino-5-ureidopentanoic acid
CAS Number
200344-33-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C21H23N3O5
Molecular Weight
397.4
MDL Number
MFCD00151942
PubChem ID
4224076
Melting Point
150 - 170 °C
Appearance
White powder
Optical Rotation
[a]D20 = 9 ± 1 º (C=2 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-citrulline is widely utilized in research focused on

  • Peptide Synthesis: This chemical is essential in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures for various applications in biochemistry and pharmaceuticals.
  • Drug Development: It plays a significant role in the development of peptide-based drugs, offering a pathway to design therapeutics that target specific biological processes, particularly in oncology and immunology.
  • Bioconjugation: Fmoc-D-citrulline is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Cardiovascular Health: This compound is involved in studies related to nitric oxide production, which is important for cardiovascular health, helping researchers understand and develop treatments for heart diseases.
  • Protein Engineering: It is utilized in protein engineering to modify proteins for enhanced stability and functionality, making it valuable in various industrial applications, including enzyme production and biotechnology.

Citations