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Catalog Number:
04008
CAS Number:
57133-29-6
Nα,δ-Bis-Boc-L-ornithine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Orn(Boc)-OH
Documents
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Product Information

Na,d-Bis-Boc-L-ornithine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features two Boc (tert-butyloxycarbonyl) protecting groups, which enhance its stability and reactivity, making it an ideal building block for constructing complex peptides and proteins. Its unique structure allows for selective deprotection under mild conditions, facilitating the synthesis of bioactive peptides that can be used in drug development and therapeutic applications.

Researchers appreciate Na,d-Bis-Boc-L-ornithine for its role in the development of peptide-based drugs, particularly in the fields of oncology and immunology. Its ability to serve as a precursor for various modifications enables the creation of tailored peptides with enhanced efficacy and specificity. Additionally, its compatibility with various coupling reagents and methods makes it a preferred choice for chemists looking to streamline their synthesis processes. With its robust applications in both academic and industrial settings, Na,d-Bis-Boc-L-ornithine stands out as a valuable asset for advancing peptide chemistry.

Synonyms
Boc-L-Orn(Boc)-OH
CAS Number
57133-29-6
Purity
≥ 98% (HPLC)
Molecular Formula
C15H28N2O6
Molecular Weight
332.4
MDL Number
MFCD00151882
PubChem ID
11099624
Melting Point
117-124 °C
Optical Rotation
[α]D20 = -7 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Orn(Boc)-OH
CAS Number
57133-29-6
Purity
≥ 98% (HPLC)
Molecular Formula
C15H28N2O6
Molecular Weight
332.4
MDL Number
MFCD00151882
PubChem ID
11099624
Melting Point
117-124 °C
Optical Rotation
[α]D20 = -7 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na,d-Bis-Boc-L-ornithine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic agents. Its protective Boc groups facilitate selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: In pharmaceutical research, it is used to create prodrugs that improve the bioavailability of active pharmaceutical ingredients, making medications more effective and easier for patients to use.
  • Bioconjugation: The compound is valuable in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in developing targeted drug delivery systems.
  • Protein Engineering: It is employed in the modification of proteins to enhance their stability and functionality, which is essential in creating more effective enzymes and therapeutic proteins.
  • Research in Cancer Therapeutics: The compound is being explored for its potential in cancer treatment, particularly in designing inhibitors that target specific pathways involved in tumor growth.

Citations