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Catalog Number:
03963
CAS Number:
56612-88-5
Boc-L-citrulline 4-nitrophenyl ester
Purity:
≥ 98% (TLC)
Synonym(s):
Boc-L-Cit-ONp, (S)-2-Boc-amino-5-ureidopentanoic acid 4-nitrophenylester
Documents
$115.90 /250MG
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Product Information

Boc-L-citrulline 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal building block for the synthesis of complex peptides. Its unique structure, characterized by the 4-nitrophenyl ester, allows for selective reactions, facilitating the introduction of various functional groups. Researchers in the fields of medicinal chemistry and biochemistry often employ Boc-L-citrulline 4-nitrophenyl ester in the development of therapeutics targeting cardiovascular diseases and metabolic disorders, as citrulline plays a crucial role in nitric oxide production and amino acid metabolism.

The compound's ability to undergo deprotection under mild conditions further enhances its appeal, allowing for straightforward incorporation into larger peptide sequences. Its applications extend to the synthesis of cyclic peptides and other bioactive molecules, showcasing its potential in advancing drug discovery and development. With its favorable properties and practical uses, Boc-L-citrulline 4-nitrophenyl ester is an essential tool for researchers aiming to innovate in the pharmaceutical and biotechnology sectors.

Synonyms
Boc-L-Cit-ONp, (S)-2-Boc-amino-5-ureidopentanoic acid 4-nitrophenylester
CAS Number
56612-88-5
Purity
≥ 98% (TLC)
Molecular Formula
C17H24N4O7
Molecular Weight
396.41
MDL Number
MFCD00076998
PubChem ID
76111562
Melting Point
94 - 96 °C
Appearance
Red-brown powder
Optical Rotation
[a]D24 = - 22 ± 1 º (C=1% in Acetone)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Cit-ONp, (S)-2-Boc-amino-5-ureidopentanoic acid 4-nitrophenylester
CAS Number
56612-88-5
Purity
≥ 98% (TLC)
Molecular Formula
C17H24N4O7
Molecular Weight
396.41
MDL Number
MFCD00076998
PubChem ID
76111562
Melting Point
94 - 96 °C
Appearance
Red-brown powder
Optical Rotation
[a]D24 = - 22 ± 1 º (C=1% in Acetone)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-citrulline 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key intermediate in the synthesis of peptides, particularly in the development of therapeutic agents. Its protective group allows for selective reactions, enhancing yield and purity.
  • Drug Development: In pharmaceutical research, it is used to create novel drug candidates targeting various diseases, including cardiovascular and metabolic disorders, by modifying amino acid sequences for improved efficacy.
  • Bioconjugation: The compound is employed in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Diagnostics: It can be used in the formulation of diagnostic agents, particularly in assays that require specific binding interactions, improving the sensitivity and specificity of tests.
  • Research on Nitric Oxide Production: As a derivative of citrulline, it plays a role in studies investigating nitric oxide synthesis, which is crucial for understanding various physiological processes and potential therapeutic targets.

Citations