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Catalog Number:
02719
CAS Number:
150828-96-9
Nα-Boc-Nδ-Fmoc-L-ornithine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Orn(Fmoc)-OH
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Product Information

Na-Boc-Nd-Fmoc-L-ornithine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to facilitate the formation of peptide bonds, making it an essential building block for the creation of complex peptides and proteins. Its unique structure, featuring both Boc (tert-butyloxycarbonyl) and Fmoc (9-fluorenylmethyloxycarbonyl) protecting groups, allows for selective deprotection, which is vital for the synthesis of peptides with specific sequences and functionalities. Researchers have successfully utilized Na-Boc-Nd-Fmoc-L-ornithine in the development of therapeutic peptides, showcasing its potential in drug formulation and delivery systems.

In addition to its applications in peptide synthesis, Na-Boc-Nd-Fmoc-L-ornithine is also recognized for its stability and compatibility with various coupling reagents, making it an ideal choice for both academic and industrial research settings. Its ability to enhance the solubility of peptides further supports its use in formulations where bioavailability is critical. As a result, this compound is increasingly being adopted in pharmaceutical research, particularly in the development of peptide-based therapeutics that target a range of diseases.

Synonyms
Boc-L-Orn(Fmoc)-OH
CAS Number
150828-96-9
Purity
≥ 99% (HPLC)
Molecular Formula
C25H30N2O6
Molecular Weight
454.53
MDL Number
MFCD00080279
PubChem ID
3644459
Melting Point
147-153 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -4 ± 1.5º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Orn(Fmoc)-OH
CAS Number
150828-96-9
Purity
≥ 99% (HPLC)
Molecular Formula
C25H30N2O6
Molecular Weight
454.53
MDL Number
MFCD00080279
PubChem ID
3644459
Melting Point
147-153 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -4 ± 1.5º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nd-Fmoc-L-ornithine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic proteins and vaccines.
  • Drug Development: It plays a significant role in the pharmaceutical industry for creating novel drug candidates, especially in targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach drugs or imaging agents to biomolecules, enhancing their efficacy and specificity.
  • Research in Cancer Therapy: It is applied in studies aimed at developing targeted cancer therapies, leveraging its ability to modify peptides for improved tumor targeting.
  • Protein Engineering: This chemical is instrumental in protein engineering, enabling scientists to design proteins with enhanced stability and functionality for various applications.

Citations